When stiffness matters: mechanosensing in heart development and disease
During embryonic morphogenesis, the heart undergoes a complex series of cellular
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …
Lattice-Boltzmann modelling for inertial particle microfluidics applications-a tutorial review
Inertial particle microfluidics (IPMF) is an emerging technology for the manipulation and
separation of microparticles and biological cells. Since the flow physics of IPMF is complex …
separation of microparticles and biological cells. Since the flow physics of IPMF is complex …
Crosslinking of fibrous hydrogels
In contrast to most synthetic hydrogels, biological gels are made of fibrous networks. This
architecture gives rise to unique properties, like low concentration, high porosity gels with a …
architecture gives rise to unique properties, like low concentration, high porosity gels with a …
Cancer cells become less deformable and more invasive with activation of β-adrenergic signaling
Invasion by cancer cells is a crucial step in metastasis. An oversimplified view in the
literature is that cancer cells become more deformable as they become more invasive. β …
literature is that cancer cells become more deformable as they become more invasive. β …
Regulation of actin bundle mechanics and structure by intracellular environmental factors
The mechanical and structural properties of actin cytoskeleton drive various cellular
processes, including structural support of the plasma membrane and cellular motility. Actin …
processes, including structural support of the plasma membrane and cellular motility. Actin …
Charge-dependent interactions of monomeric and filamentous actin with lipid bilayers
The cytoskeletal protein actin polymerizes into filaments that are essential for the
mechanical stability of mammalian cells. In vitro experiments showed that direct interactions …
mechanical stability of mammalian cells. In vitro experiments showed that direct interactions …
Morphological transformation and force generation of active cytoskeletal networks
Cells assemble numerous types of actomyosin bundles that generate contractile forces for
biological processes, such as cytokinesis and cell migration. One example of contractile …
biological processes, such as cytokinesis and cell migration. One example of contractile …
Probing eukaryotic cell mechanics via mesoscopic simulations
K Lykov, Y Nematbakhsh, M Shang… - PLoS computational …, 2017 - journals.plos.org
Cell mechanics has proven to be important in many biological processes. Although there is
a number of experimental techniques which allow us to study mechanical properties of cell …
a number of experimental techniques which allow us to study mechanical properties of cell …
Biomechanics of cells and subcellular components: a comprehensive review of computational models and applications
Cells are a fundamental structural, functional and biological unit for all living organisms. Up
till now, considerable efforts have been made to study the responses of single cells and …
till now, considerable efforts have been made to study the responses of single cells and …
Modeling and simulations of the dynamic behaviors of actin-based cytoskeletal networks
The cytoskeleton, a dynamic network of biopolymers with their associated cross-linking and
motor proteins, is responsible for stabilizing cell shape and driving cell movement. This …
motor proteins, is responsible for stabilizing cell shape and driving cell movement. This …