The role of prolactin in central nervous system inflammation

E Ramos-Martinez, I Ramos-Martínez… - Reviews in the …, 2021 - degruyter.com
Prolactin has been shown to favor both the activation and suppression of the microglia and
astrocytes, as well as the release of inflammatory and anti-inflammatory cytokines. Prolactin …

Regulation of blood vessels by prolactin and vasoinhibins

C Clapp, S Thebault, Y Macotela… - Recent advances in …, 2014 - Springer
Prolactin (PRL) stimulates the growth of new blood vessels (angiogenesis) either directly
through actions on endothelial cells or indirectly by upregulating proangiogenic factors like …

Single-cell transcriptomics reveals maturation of transplanted stem cell–derived retinal pigment epithelial cells toward native state

BH Parikh, P Blakeley, K Regha, Z Liu, B Yang… - Proceedings of the …, 2023 - pnas.org
Transplantation of stem cell–derived retinal pigment epithelial (RPE) cells is considered a
viable therapeutic option for age-related macular degeneration (AMD). Several landmark …

Prolactin is an Endogenous Antioxidant Factor in Astrocytes That Limits Oxidative Stress-Induced Astrocytic Cell Death via the STAT3/NRF2 Signaling Pathway

M Ulloa, F Macías, C Clapp… - Neurochemical …, 2024 - Springer
Oxidative stress-induced death of neurons and astrocytes contributes to the pathogenesis of
numerous neurodegenerative diseases. While significant progress has been made in …

Prolactin and its altered action in Alzheimer's disease and Parkinson's disease

H Duc Nguyen, B Pal Yu, NHM Hoang, WH Jo… - …, 2022 - karger.com
Background: Prolactin (PRL) is one of the most diverse pituitary hormones and is known to
modulate normal neuronal function and neurodegenerative conditions. Many studies have …

Prolactin prevents mitochondrial dysfunction induced by glutamate excitotoxicity in hippocampal neurons

NA Rivero-Segura, MI Coronado-Mares… - Neuroscience …, 2019 - Elsevier
Prolactin (PRL) is a pleiotropic hormone secreted by several cells and tissues in the body,
such as mammary glands, T-lymphocytes, hypothalamus, among others. This hormone …

Decoding signaling pathways involved in prolactin-induced neuroprotection: A review

G Molina-Salinas, NA Rivero-Segura… - Frontiers in …, 2021 - Elsevier
It has been well recognized that prolactin (PRL), a pleiotropic hormone, has many functions
in the brain, such as maternal behavior, neurogenesis, and neuronal plasticity, among …

Small RNA sequencing of aqueous humor and plasma in patients with primary open-angle glaucoma

WHG Hubens, J Krauskopf… - … & visual science, 2021 - iovs.arvojournals.org
Purpose: Identify differentially expressed microRNAs (miRNAs) in aqueous humor (AH) and
blood of primary open-angle glaucoma (POAG) patients by using small RNA sequencing …

Effect of prolactin on cytotoxicity and oxidative stress in ovine ovarian granulosa cells

R Yang, S Zhang, C Duan, Y Guo, X Shan, X Zhang… - PeerJ, 2023 - peerj.com
Background Prolactin (PRL) has been reported to be associated with oxidative stress, which
is an important contributor leading to cell apoptosis. However, little is known about the …

Carvacrol protects the ARPE19 retinal pigment epithelial cells against high glucose-induced oxidative stress, apoptosis, and inflammation by suppressing the TRPM2 …

H Daldal, M Nazıroğlu - Graefe's Archive for Clinical and Experimental …, 2022 - Springer
Purpose The concentration of plasma high glucose (HGu) in diabetes mellitus (DM) induces
the retinal pigment epithelial cell (ARPE19) death via the increase of inflammation, cytosolic …