RNA secondary structures have proven essential for understanding the regulatory functions
performed by RNA such as microRNAs, bacterial small RNAs, or riboswitches. This success …

Motion planning is a fundamental problem in robotics that has motivated research since
more than three decades ago. A large variety of algorithms have been proposed to compute …

Motivation: Motion is inherent in molecular interactions. Molecular flexibility must be taken
into account in order to develop accurate computational techniques for predicting …

This paper presents a new sampling method for motion planning that can generate
configurations more uniformly distributed on C-obstacle surfaces than prior approaches …

Dynamic processes involving macromolecular complexes are essential to cell function.
These processes take place over a wide variety of length scales from nanometers to …

Protein motions, ranging from molecular flexibility to large-scale conformational change,
play an essential role in many biochemical processes. Despite the explosion in our …

Lipase from Burkholderia cepacia (BCL) has proven to be a very useful biocatalyst for the
resolution of 2‐substituted racemic acid derivatives, which are important chiral building …

Abstract Domain swap** is a process where two (or more) protein molecules form a dimer
(or higher oligomer) by exchanging an identical domain. In this article, based on the …

The term RNA folding is often used synonymously with the prediction of equilibrium
structures. Yet many RNA s function thanks to their ability to undergo structural changes. In …

We present a general computational approach to simulate RNA folding kinetics that can be
used to extract population kinetics, folding rates and the formation of particular substructures …