Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Advances in magnetic nanoparticles for biomedical applications

VF Cardoso, A Francesko, C Ribeiro… - Advanced …, 2018 - Wiley Online Library
Magnetic nanoparticles (NPs) are emerging as an important class of biomedical functional
nanomaterials in areas such as hyperthermia, drug release, tissue engineering, theranostic …

Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review

MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Liposomes as carriers of hydrophilic small molecule drugs: strategies to enhance encapsulation and delivery

JO Eloy, MC de Souza, R Petrilli, JPA Barcellos… - Colloids and surfaces B …, 2014 - Elsevier
Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

Perspective of Fe3O4 Nanoparticles Role in Biomedical Applications

MR Ghazanfari, M Kashefi, SF Shams… - Biochemistry …, 2016 - Wiley Online Library
In recent years, although many review articles have been presented about bioapplications of
magnetic nanoparticles by some research groups with different expertise such as chemistry …

Liposome-polymer complex for drug delivery system and vaccine stabilization

AK Umar, N Wathoni, JH Zothantluanga, S Das… - Heliyon, 2022 - cell.com
Liposomes have been used extensively as micro-and nanocarriers for hydrophobic or
hydrophilic molecules. However, conventional liposomes are biodegradable and quickly …

Single-versus dual-targeted nanoparticles with folic acid and biotin for anticancer drug delivery

M Jurczyk, K Jelonek, M Musiał-Kulik, A Beberok… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the major causes of death worldwide and its treatment remains very
challenging. The effectiveness of cancer therapy significantly depends upon tumour-specific …

Tumor microenvironment targeted nanotherapy

C Fernandes, D Suares, MC Yergeri - Frontiers in pharmacology, 2018 - frontiersin.org
Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …

An overview and bibliometric analysis on the colorectal cancer therapy by magnetic functionalized nanoparticles for the responsive and targeted drug delivery

M Darroudi, M Gholami, M Rezayi… - Journal of …, 2021 - Springer
With the growing demands for personalized medicine and medical devices, nanomedicine is
a modern scientific field, and research continues to apply nanomaterials for therapeutic and …

[HTML][HTML] Functionalization of nanoparticulate drug delivery systems and its influence in cancer therapy

TA Seidu, PT Kutoka, DO Asante, MA Farooq… - Pharmaceutics, 2022 - mdpi.com
Research into the application of nanocarriers in the delivery of cancer-fighting drugs has
been a promising research area for decades. On the other hand, their cytotoxic effects on …