Programmed stimuli-responsive carbon dot-nanogel hybrids for imaging-guided enhanced tumor phototherapy

C Zhao, S Sun, S Li, A Lv, Q Chen, K Jiang… - … Applied Materials & …, 2022 - ACS Publications
For harmonizing the contradiction of nanotheranostic agents between enhanced tumor
accumulation and penetration, efficient cell internalization and fast elimination are key …

[HTML][HTML] Advanced photodynamic therapy with an engineered M13 phage targeting EGFR: Mitochondrial localization and autophagy induction in ovarian cancer cell …

B Bortot, M Apollonio, G Baj, L Andolfi, L Zupin… - Free Radical Biology …, 2022 - Elsevier
Photodynamic therapy (PDT) is a potential synergistic approach to chemotherapy for treating
ovarian cancer, the most lethal gynecologic malignancy. Here we used M13 bacteriophage …

[HTML][HTML] Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy

A Cantelli, F Piro, P Pecchini, M Di Giosia… - … of Photochemistry and …, 2020 - Elsevier
Photodynamic therapy (PDT) is considered a very promising therapeutic modality for
antimicrobial therapy. Although several studies have demonstrated that Gram-positive …

Carrying temoporfin with human serum albumin: A new perspective for photodynamic application in head and neck cancer

EJ Mattioli, L Ulfo, A Marconi, V Pellicioni… - Biomolecules, 2022 - mdpi.com
Temoporfin (mTHPC) is approved in Europe for the photodynamic treatment of head and
neck squamous cell carcinoma (HNSCC). Although it has a promising profile, its lipophilic …

Dissecting the interactions between chlorin e6 and human serum albumin

A Marconi, EJ Mattioli, F Ingargiola, G Giugliano… - Molecules, 2023 - mdpi.com
Chlorin e6 (Ce6) is among the most used sensitizers in photodynamic (PDT) and
sonodynamic (SDT) therapy; its low solubility in water, however, hampers its clinical …

Putting a “C60 Ball” and Chain to Chlorin e6 Improves Its Cellular Uptake and Photodynamic Performances

M Di Sante, A Kaltenbrunner, M Lombardo, A Danielli… - Pharmaceuticals, 2023 - mdpi.com
Chlorin e6 (Ce6) and fullerene (C60) are among the most used photosensitizers (PSs) for
photodynamic therapy (PDT). Through the combination of the chemical and photophysical …

Identification of blood transport proteins to carry temoporfin: a domino approach from virtual screening to synthesis and in vitro PDT testing

A Marconi, G Giugliano, M Di Giosia, TD Marforio… - Pharmaceutics, 2023 - mdpi.com
Temoporfin (mTHPC) is one of the most promising photosensitizers used in photodynamic
therapy (PDT). Despite its clinical use, the lipophilic character of mTHPC still hampers the …

Rational design of an artificial hydrolytic nuclease by introduction of a sodium copper chlorophyllin in L29E myoglobin

Y Dong, YM Chen, XJ Kong, SQ Gao, JJ Lang… - Journal of Inorganic …, 2022 - Elsevier
Heme proteins have recently emerged as promising artificial metalloenzymes for catalyzing
diverse reactions. In this report, L29E Mb, a single mutant of myoglobin (Mb), was …

Advanced photodynamic therapy with an engineered M13 phage targeting EGFR: Mitochondrial localization and autophagy induction in ovarian cancer cell lines

B Barbara, M Apollonio, G Baj, L Andolfi, L Zupin… - 2022 - qspace.qu.edu.qa
Photodynamic therapy (PDT) is a potential synergistic approach to chemotherapy for treating
ovarian cancer, the most lethal gynecologic malignancy. Here we used M13 bacteriophage …