Mitochondrial proteins: from biogenesis to functional networks
Mitochondria are essential for the viability of eukaryotic cells as they perform crucial
functions in bioenergetics, metabolism and signalling and have been associated with …
functions in bioenergetics, metabolism and signalling and have been associated with …
Mitochondrial machineries for protein import and assembly
Mitochondria are essential organelles with numerous functions in cellular metabolism and
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …
Mitochondrial protein transport: Versatility of translocases and mechanisms
Biogenesis of mitochondria requires the import of approximately 1,000 different precursor
proteins into and across the mitochondrial membranes. Mitochondria exhibit a wide variety …
proteins into and across the mitochondrial membranes. Mitochondria exhibit a wide variety …
Mitochondrial protein import: from proteomics to functional mechanisms
Mitochondria contain∼ 1,000 different proteins, most of which are imported from the cytosol.
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …
[HTML][HTML] The protein import machinery of mitochondria—a regulatory hub in metabolism, stress, and disease
Mitochondria fulfill central functions in bioenergetics, metabolism, and apoptosis. They
import more than 1,000 different proteins from the cytosol. It had been assumed that the …
import more than 1,000 different proteins from the cytosol. It had been assumed that the …
[BOOK][B] The structure of biological membranes
PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …
biochemistry. Now more than ever, it is essential to update our current understanding of …
Atomic structure of human TOM core complex
W Wang, X Chen, L Zhang, J Yi, Q Ma, J Yin, W Zhuo… - Cell discovery, 2020 - nature.com
The translocase of the outer mitochondrial membrane (TOM) complex is the main entry gate
for mitochondrial precursor proteins synthesized on cytosolic ribosomes. Here we report the …
for mitochondrial precursor proteins synthesized on cytosolic ribosomes. Here we report the …
[HTML][HTML] Mitochondrial protein import: common principles and physiological networks
Most mitochondrial proteins are encoded in the nucleus. They are synthesized as precursor
forms in the cytosol and must be imported into mitochondria with the help of different protein …
forms in the cytosol and must be imported into mitochondria with the help of different protein …
Mitochondrial complexome and import network
Mitochondria perform crucial functions in cellular metabolism, protein and lipid biogenesis,
quality control, and signaling. The systematic analysis of protein complexes and interaction …
quality control, and signaling. The systematic analysis of protein complexes and interaction …
Reciprocal roles of Tom7 and OMA1 during mitochondrial import and activation of PINK1
Mutations in PTEN-induced kinase 1 (PINK1) can cause recessive early-onset Parkinson's
disease (PD). Import arrest results in PINK1 kinase activation specifically on damaged …
disease (PD). Import arrest results in PINK1 kinase activation specifically on damaged …