The phasor approach to fluorescence lifetime imaging has become a common method to
analyze complicated fluorescence signals from biological samples. The appeal of the …

Conspectus Any chemist studying the interaction of molecules with lipid assemblies will
eventually be confronted by the topic of membrane bilayer heterogeneity and may ultimately …

Membrane wetting by biomolecular condensates recently emerged as a key phenomenon in
cell biology, playing an important role in a diverse range of processes across different …

Environmental polarity is an important factor that drives biomolecular interactions to regulate
cell function. Herein, a general method of using the fluorogenic probe NTPAN‐MI is reported …

Lipid packing is a crucial feature of cellular membranes. Quantitative analysis of membrane
lipid packing can be achieved using polarity sensitive probes whose emission spectrum …

The plasma membrane has a highly asymmetric distribution of lipids and contains dynamic
nanodomains many of which are liquid entities surrounded by a second, slightly different …

Physicochemical properties of the plasma membrane have been shown to play an important
role in cellular functionality. Among those properties, the molecular order of the lipids, or the …

The eye is an ideal organ for imaging by a multi-photon excitation approach, because ocular
tissues such as the sclera, cornea, lens and neurosensory retina, are highly transparent to …

High-resolution imaging techniques capable of detecting identifiable endogenous
fluorophores in the eye along with genetic testing will dramatically improve diagnostic …

Using LAURDAN spectral imaging and spectral phasor analysis we concurrently studied the
growth and hydration state of subcellular organelles (lamellar body-like, LB-like) from live …