Single-cell RNA sequencing technologies and bioinformatics pipelines
Rapid progress in the development of next-generation sequencing (NGS) technologies in
recent years has provided many valuable insights into complex biological systems, ranging …
recent years has provided many valuable insights into complex biological systems, ranging …
Subtypes of preeclampsia: recognition and determining clinical usefulness
The concept that preeclampsia is a multisystemic syndrome is appreciated in both research
and clinical care. Our understanding of pathophysiology recognizes the role of inflammation …
and clinical care. Our understanding of pathophysiology recognizes the role of inflammation …
Complex heatmap visualization
Z Gu - Imeta, 2022 - Wiley Online Library
Heatmap is a widely used statistical visualization method on matrix‐like data to reveal
similar patterns shared by subsets of rows and columns. In the R programming language …
similar patterns shared by subsets of rows and columns. In the R programming language …
Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer
F Schettini, N Chic, F Brasó-Maristany, L Paré… - NPJ breast …, 2021 - nature.com
Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative
breast cancer (BC) with low HER2 expression (ie, 1+ or 2+ and lack of ERBB2 amplification) …
breast cancer (BC) with low HER2 expression (ie, 1+ or 2+ and lack of ERBB2 amplification) …
[HTML][HTML] A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs,
and disease states are connected by virtue of common gene-expression signatures. Here …
and disease states are connected by virtue of common gene-expression signatures. Here …
Liver injury after SARS‐CoV‐2 vaccination: Features of immune‐mediated hepatitis, role of corticosteroid therapy and outcome
Conclusions SARS‐CoV‐2 vaccination can be associated with liver injury. Corticosteroid
therapy may be beneficial in those with immune‐mediated features or severe hepatitis …
therapy may be beneficial in those with immune‐mediated features or severe hepatitis …