Single-cell RNA sequencing technologies and bioinformatics pipelines

B Hwang, JH Lee, D Bang - Experimental & molecular medicine, 2018 - nature.com
Rapid progress in the development of next-generation sequencing (NGS) technologies in
recent years has provided many valuable insights into complex biological systems, ranging …

Subtypes of preeclampsia: recognition and determining clinical usefulness

JM Roberts, JW Rich-Edwards, TF McElrath… - …, 2021 - Am Heart Assoc
The concept that preeclampsia is a multisystemic syndrome is appreciated in both research
and clinical care. Our understanding of pathophysiology recognizes the role of inflammation …

Complex heatmap visualization

Z Gu - Imeta, 2022 - Wiley Online Library
Heatmap is a widely used statistical visualization method on matrix‐like data to reveal
similar patterns shared by subsets of rows and columns. In the R programming language …

Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer

F Schettini, N Chic, F Brasó-Maristany, L Paré… - NPJ breast …, 2021 - nature.com
Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative
breast cancer (BC) with low HER2 expression (ie, 1+ or 2+ and lack of ERBB2 amplification) …

[HTML][HTML] A next generation connectivity map: L1000 platform and the first 1,000,000 profiles

A Subramanian, R Narayan, SM Corsello, DD Peck… - Cell, 2017 - cell.com
We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs,
and disease states are connected by virtue of common gene-expression signatures. Here …

Liver injury after SARS‐CoV‐2 vaccination: Features of immune‐mediated hepatitis, role of corticosteroid therapy and outcome

C Efe, AV Kulkarni, BT Beretta‐Piccoli, B Magro… - Hepatology, 2022 - journals.lww.com
Conclusions SARS‐CoV‐2 vaccination can be associated with liver injury. Corticosteroid
therapy may be beneficial in those with immune‐mediated features or severe hepatitis …