The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies

C Heim, CB Nemeroff - Biological psychiatry, 2001 - Elsevier
Epidemiologic studies indicate that children exposed to early adverse experiences are at
increased risk for the development of depression, anxiety disorders, or both. Persistent …

Neural mechanisms of the cognitive model of depression

SG Disner, CG Beevers, EAP Haigh… - Nature Reviews …, 2011 - nature.com
In the 40 years since Aaron Beck first proposed his cognitive model of depression, the
elements of this model—biased attention, biased processing, biased thoughts and …

No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples

R Border, EC Johnson, LM Evans… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Interest in candidate gene and candidate gene-by-environment interaction
hypotheses regarding major depressive disorder remains strong despite controversy …

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

KP Lesch, D Bengel, A Heils, SZ Sabol, BD Greenberg… - Science, 1996 - science.org
Transporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been
implicated in anxiety in humans and animal models and is the site of action of widely used …

[HTML][HTML] Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs

D da Luz Scheffer, A Latini - … et Biophysica Acta (BBA)-Molecular Basis of …, 2020 - Elsevier
A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Allelic variation of human serotonin transporter gene expression

A Heils, A Teufel, S Petri, G Stöber… - Journal of …, 1996 - Wiley Online Library
Mood, emotion, cognition, and motor functions as well as circadian and neuroendocrine
rhythms, including food intake, sleep, and reproductive activity, are modulated by the …

The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment

DL Musselman, DL Evans… - Archives of general …, 1998 - jamanetwork.com
This article reviews the burgeoning literature on the relationship of mood disorders and
heart disease. Major depression and depressive symptoms, although commonly …

The effects of probiotics on depressive symptoms in humans: a systematic review

CJK Wallace, R Milev - Annals of general psychiatry, 2017 - Springer
Background Patients suffering from depression experience significant mood, anxiety, and
cognitive symptoms. Currently, most antidepressants work by altering neurotransmitter …

Chronic pain-associated depression: antecedent or consequence of chronic pain? A review

DA Fishbain, R Cutler, HL Rosomoff… - The Clinical journal of …, 1997 - journals.lww.com
Objective: To determine the current status for the association of chronic pain and depression
and to review the evidence for whether depression is an antecedent or consequence of …

The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat

L Desbonnet, L Garrett, G Clarke, J Bienenstock… - Journal of psychiatric …, 2008 - Elsevier
It is becoming increasingly apparent that probiotics are important to the health of the host.
The absence of probiotic bacteria in the gut can have adverse effects not only locally in the …