Management of menopause: a view towards prevention

RA Lobo, A Gompel - The Lancet Diabetes & Endocrinology, 2022‏ - thelancet.com
Women spend approximately one-third of their lives with menopause, which occurs around
50 years of age. It is now appreciated that several important metabolic and cardiovascular …

Current understanding of the etiology, symptomatology, and treatment options in premature ovarian insufficiency (POI)

B Ishizuka - Frontiers in endocrinology, 2021‏ - frontiersin.org
Premature ovarian insufficiency (POI) occurs in at least 1% of all women and causes life-
long health problems and psychological stress. Infertility caused by POI used to be …

The 2022 hormone therapy position statement of the North American Menopause Society

SS Faubion, CJ Crandall, L Davis… - …, 2022‏ - ingentaconnect.com
“The 2022 Hormone Therapy Position Statement of The North American Menopause
Society”(NAMS) updates “The 2017 Hormone Therapy Position Statement of The North …

Differences between women and men in incidence rates of dementia and Alzheimer's disease

CR Beam, C Kaneshiro, JY Jang… - Journal of …, 2018‏ - content.iospress.com
In the following brief report, we examined gender differences in incidence rates of any
dementia, Alzheimer's disease (AD) alone, and non-Alzheimer's dementia alone in 16,926 …

[HTML][HTML] Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer's disease and dementia

M Nerattini, S Jett, C Andy, C Carlton… - Frontiers in aging …, 2023‏ - frontiersin.org
Introduction Despite a large preclinical literature demonstrating neuroprotective effects of
estrogen, use of menopausal hormone therapy (HT) for Alzheimer's disease (AD) risk …

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

L Mosconi, V Berti, J Dyke, E Schelbaum, S Jett… - Scientific reports, 2021‏ - nature.com
All women undergo the menopause transition (MT), a neuro-endocrinological process that
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …

Long-term health consequences of premature or early menopause and considerations for management

SS Faubion, CL Kuhle, LT Shuster, WA Rocca - Climacteric, 2015‏ - Taylor & Francis
Aim To review the current evidence concerning the long-term harmful effects of premature or
early menopause, and to discuss some of the clinical implications. Material and methods …

Endogenous and exogenous estrogen exposures: how women's reproductive health can drive brain aging and inform Alzheimer's prevention

S Jett, N Malviya, E Schelbaum, G Jang… - Frontiers in Aging …, 2022‏ - frontiersin.org
After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …

Perimenopause as a neurological transition state

RD Brinton, J Yao, F Yin, WJ Mack… - Nature reviews …, 2015‏ - nature.com
Perimenopause is a midlife transition state experienced by women that occurs in the context
of a fully functioning neurological system and results in reproductive senescence. Although …

Estrogen, stress, and depression: cognitive and biological interactions

KM Albert, PA Newhouse - Annual review of clinical psychology, 2019‏ - annualreviews.org
This article reviews the interactions of estrogen changes and psychosocial stress in
contributing to vulnerability to major depressive disorder (MDD) in women. Estrogen …