Bioactive materials for bone regeneration: biomolecules and delivery systems
A Szwed-Georgiou, P Płociński… - ACS Biomaterials …, 2023 - ACS Publications
Novel tissue regeneration strategies are constantly being developed worldwide. Research
on bone regeneration is noteworthy, as many promising new approaches have been …
on bone regeneration is noteworthy, as many promising new approaches have been …
Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery
Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …
[HTML][HTML] Cytotoxic impacts of linear and branched polyethylenimine nanostructures in a431 cells
Methods In this current study, cytogenomic impacts of 25 kD linear and branched PEI (LPEI
and BPEI, respectively) in A431 cells are reported to address possible mechanism for …
and BPEI, respectively) in A431 cells are reported to address possible mechanism for …
Polyplex evolution: understanding biology, optimizing performance
Polyethylenimine (PEI) is a gold standard polycationic transfectant. However, the highly
efficient transfecting activity of PEI and many of its derivatives is accompanied by serious …
efficient transfecting activity of PEI and many of its derivatives is accompanied by serious …
[HTML][HTML] Novel delivery system for natural products: Nano-curcumin formulations
Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal
pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis …
pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis …
Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells
Background Surface charge and oxidative stress are often hypothesized to be important
factors in cytotoxicity of nanoparticles. However, the role of these factors is not well …
factors in cytotoxicity of nanoparticles. However, the role of these factors is not well …
Polycation cytotoxicity: a delicate matter for nucleic acid therapy—focus on polyethylenimine
This article provides a critical assessment of the major challenges facing nucleic acid
therapeutics, focusing on the safety and efficacy of delivery strategies using synthetic …
therapeutics, focusing on the safety and efficacy of delivery strategies using synthetic …
Understanding the toxicity of carbon nanotubes in the environment is crucial to the control of nanomaterials in producing and processing and the assessment of health …
J Du, S Wang, H You, X Zhao - Environmental Toxicology and …, 2013 - Elsevier
With the development and application of carbon nanotubes (CNTs), the potential hazards of
CNTs to biological systems and the environment are getting more and more attention. This …
CNTs to biological systems and the environment are getting more and more attention. This …
Cationic polymer optimization for efficient gene delivery
X Sun, N Zhang - Mini reviews in medicinal chemistry, 2010 - ingentaconnect.com
The polyplexes which are formed between cationic polymers and DNA through electrostatic
interactions and thus known as polycation/DNA complexes, are by far the most widely used …
interactions and thus known as polycation/DNA complexes, are by far the most widely used …
Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer
E Bertrand, C Gonçalves, L Billiet, JP Gomez… - Chemical …, 2011 - pubs.rsc.org
A series of linear polyethylenimine (lPEI) substituted with histidine residue (His-lPEI) was
synthesized using the Michael reaction in order to provide new highly efficient vectors for …
synthesized using the Michael reaction in order to provide new highly efficient vectors for …