Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease
Progression of chronic liver disease is precipitated by hepatocyte loss, inflammation and
fibrosis. This process results in the loss of critical hepatic functions, increasing morbidity and …
fibrosis. This process results in the loss of critical hepatic functions, increasing morbidity and …
Fecal metabolite profiling identifies liver transplant recipients at risk for postoperative infection
Metabolites produced by the intestinal microbiome modulate mucosal immune defenses and
optimize epithelial barrier function. Intestinal dysbiosis, including loss of intestinal …
optimize epithelial barrier function. Intestinal dysbiosis, including loss of intestinal …
Ecological dynamics of Enterobacteriaceae in the human gut microbiome across global populations
Gut bacteria from the Enterobacteriaceae family are a major cause of opportunistic infections
worldwide. Given their prevalence among healthy human gut microbiomes, interspecies …
worldwide. Given their prevalence among healthy human gut microbiomes, interspecies …
Klebsiella oxytoca facilitates microbiome recovery via antibiotic degradation and restores colonization resistance in a diet-dependent manner
Competition among bacteria for carbohydrates is pivotal for colonization resistance (CR).
However, the impact of Western-style diets on CR remains unclear. Here we show how the …
However, the impact of Western-style diets on CR remains unclear. Here we show how the …
Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms
The Klebsiella oxytoca species complex is part of the human microbiome, especially during
infancy and childhood. K. oxytoca species complex strains can produce enterotoxins …
infancy and childhood. K. oxytoca species complex strains can produce enterotoxins …
[HTML][HTML] Microbiota and metabolic adaptation shape Staphylococcus aureus virulence and antimicrobial resistance during intestinal colonization
Depletion of microbiota increases susceptibility to gastrointestinal colonization and
subsequent infection by opportunistic pathogens such as methicillin-resistant …
subsequent infection by opportunistic pathogens such as methicillin-resistant …
Gut protective Klebsiella species promotes microbiota recovery and pathobiont clearance while preventing inflammation
The microbiota inhabiting the mammalian gut serves as a protective barrier against
pathogen invasion through a mechanism known as colonization resistance. Antibiotic …
pathogen invasion through a mechanism known as colonization resistance. Antibiotic …
Sugar-rich foods exacerbate antibiotic-induced microbiome injury
Intestinal microbiota composition is implicated in several diseases; understanding the
factors that influence it are key to elucidating host-commensal interactions and to designing …
factors that influence it are key to elucidating host-commensal interactions and to designing …