The excellent biocompatibility and unique inclusion capability as well as powerful
functionalization capacity of cyclodextrins and their derivatives make them especially …

Successful cancer management depends on accurate diagnostics along with specific
treatment protocols. Current diagnostic techniques need to be improved to provide earlier …

Non-viral gene-delivery systems are safer to use and easier to produce than viral vectors,
but their comparatively low transfection efficiency has limited their applications. Co-delivery …

RNAi technology has brought a new category of treatments for various diseases including
genetic diseases, viral diseases, and cancer. Despite the great versatility of RNAi that can …

Gene therapy covers a broad spectrum of applications, from gene replacement and
knockdown for genetic or acquired diseases such as cancer, to vaccination, each with …

Non-viral vectors continue to be an attractive alternative to viral vectors due to their safety,
versatility and ease of preparation and scale-up. Over the past few years, investigators have …

Traditional chemotherapy used today at clinics is mainly inherited from the thinking and
designs made four decades ago when the Cancer War was declared. The potency of those …

Selective targeting of ligand-targeted liposomes containing anticancer drugs or therapeutic
genes to cell surface receptors expressed on cancer cells is a recognized strategy for …

Numerous nanoparticle (NP) drug delivery vehicles have emerged during the past two
decades including, for example, polymeric NPs, block copolymer micelles, liposomes …

The ability to deliver nucleic acids (eg, plasmid DNA, antisense oligonucleotides, siRNA)
offers the potential to develop potent vaccines and novel therapeutics. However, nucleic …