The eukaryotic intestinal parasite Giardia intestinalis was first described in 1681, when
Antonie van Leeuwenhoek undertook a microscopic examination of his own diarrhoeal …

Evolution of exon-intron structure of eukaryotic genes has been a matter of long-standing,
intensive debate. The introns-early concept, later rebranded 'introns first'held that protein …

Complete genomic sequences from diverse phylogenetic lineages reveal notable increases
in genome complexity from prokaryotes to multicellular eukaryotes. The changes include …

Abstract'Out-of-body'experiences (OBEs) are curious, usually brief sensations in which a
person's consciousness seems to become detached from the body and take up a remote …

The genome of the eukaryotic protist Giardia lamblia, an important human intestinal parasite,
is compact in structure and content, contains few introns or mitochondrial relics, and has …

The origins and importance of spliceosomal introns comprise one of the longest-abiding
mysteries of molecular evolution. Considerable debate remains over several aspects of the …

WRKY transcription factors, originally isolated from plants contain one or two conserved
WRKY domains, about 60 amino acid residues with the WRKYGQK sequence followed by a …

Transcription is a slow and expensive process: in eukaryotes, approximately 20 nucleotides
can be transcribed per second 1, 2 at the expense of at least two ATP molecules per …

The origin of the eukaryotic nucleus marked a seminal evolutionary transition. We propose
that the nuclear envelope's incipient function was to allow mRNA splicing, which is slow, to …

Sequencing of eukaryotic genomes allows one to address major evolutionary problems,
such as the evolution of gene structure. We compared the intron positions in 684 …