Patients living with osteoporosis are projected to increase dramatically in the next decade.
Alongside the forecasted increased societal and economic burden, we will live a crisis of …

The reconstruction of large cranial bone defects by bioactive materials without exogenous
cells or growth factors remains a substantial clinical challenge. Here, synthetic fibrous …

Bioengineered materials represent an innovative option to support the regenerative
processes of damaged tissues, with the final objective of creating a functional environment …

The regeneration of large-scale bone loss due to accidents, trauma, diseases, or tumor
resection is still a critical clinical challenge. With the development of additive manufacturing …

Lattice structures have found significant applications in the biomedical field due to their
interesting combination of mechanical and biological properties. Among these, functionally …

The design of novel biomimetic bone tissue scaffolds (BTS) using computer aided design
(CAD) technology is challenging additive manufacturing technologies. At the microstructure …

Three-dimensional (3D) printing, an additive manufacturing technique, is increasingly used
in the field of tissue engineering. The ability to create complex structures with high precision …

The dam** system ensured by the osteochondral (OC) unit is essential to deploy the
forces generated within load-bearing joints during locomotion, allowing furthermore low …

In this study, composite membrane scaffolds comprising poly (vinylidene fluoride)(PVDF)
and boron‐containing biphasic calcium phosphate (BCP) are developed using a non …

The work presents a novel thin-walled biomimetic auxetic meta-shell for patient-specific
vertebral orthopedic implants. The proposed design stemmed from the concept of an …