The dynamic structure of the estrogen receptor

R Kumar, MN Zakharov, SH Khan, R Miki… - Journal of amino …, 2011 - Wiley Online Library
The estrogen receptor (ER) mediates most of the biological effects of estrogens at the level
of gene regulation by interacting through its site‐specific DNA and with other coregulatory …

[HTML][HTML] Biological properties of ruthenium (II)/(III) complexes with flavonoids as ligands

M Małecka, A Skoczyńska, DM Goodman… - Coordination Chemistry …, 2021 - Elsevier
This review highlights the progress in the development of ruthenium (II)/(III) complexes with
flavone derivatives as potential therapeutic agents. We focused on natural hydroxyflavone …

[HTML][HTML] Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents

R Mesnage, A Phedonos, M Biserni, M Arno… - Food and Chemical …, 2017 - Elsevier
The safety, including the endocrine disruptive capability, of glyphosate-based herbicides
(GBHs) is a matter of intense debate. We evaluated the estrogenic potential of glyphosate …

Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state

KA Green, JS Carroll - Nature Reviews Cancer, 2007 - nature.com
Oestrogen receptor-α (ERα)-regulated transcription in breast cancer cells involves protein co-
factors that contribute to the regulation of chromatin structure. These include co-factors with …

Histone H2A. Z is essential for estrogen receptor signaling

N Gévry, S Hardy, PÉ Jacques, L Laflamme… - Genes & …, 2009 - genesdev.cshlp.org
Incorporation of H2A. Z into the chromatin of inactive promoters has been shown to poise
genes for their expression. Here we provide strong evidence that H2A. Z is incorporated into …

Bisphenol-S and Bisphenol-F alter mouse pancreatic β-cell ion channel expression and activity and insulin release through an estrogen receptor ERβ mediated …

L Marroqui, J Martinez-Pinna, M Castellano-Muñoz… - Chemosphere, 2021 - Elsevier
Abstract Bisphenol-S (BPS) and Bisphenol-F (BPF) are current Bisphenol-A (BPA)
substitutes. Here we used pancreatic β-cells from wild type (WT) and estrogen receptor β …

In Silico Predictions of Endocrine Disruptors Properties

M Schneider, JL Pons, G Labesse, W Bourguet - Endocrinology, 2019 - academic.oup.com
Endocrine-disrupting chemicals (EDCs) are a broad class of molecules present in our
environment that are suspected to cause adverse effects in the endocrine system by …

Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR-and structure-based virtual screening approaches

L Zhang, A Sedykh, A Tripathi, H Zhu, A Afantitis… - Toxicology and applied …, 2013 - Elsevier
Identification of endocrine disrupting chemicals is one of the important goals of
environmental chemical hazard screening. We report on the development of validated in …

Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor

Y Watanabe, H Kojima, S Takeuchi, N Uramaru… - Food and chemical …, 2013 - Elsevier
The structure-activity relationships of parabens which are widely used as preservatives for
transcriptional activities mediated by human estrogen receptor α (hERα), hERβ and …

Comprehensive assessment of estrogenic activities of parabens by in silico approach and in vitro assays

F Wei, H Cheng, N Sang - Science of The Total Environment, 2022 - Elsevier
Parabens are ubiquitous pollutants in the environment and humans due to their wide
applications in food, pharmaceuticals, and personal care products. Although the estrogenic …