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The role of microglia in diabetic retinopathy: inflammation, microvasculature defects and neurodegeneration
C Altmann, MHH Schmidt - International journal of molecular sciences, 2018 - mdpi.com
Diabetic retinopathy is a common complication of diabetes mellitus, which appears in one
third of all diabetic patients and is a prominent cause of vision loss. First discovered as a …
third of all diabetic patients and is a prominent cause of vision loss. First discovered as a …
The OCT angular sign of Henle fiber layer (HFL) hyperreflectivity (ASHH) and the pathoanatomy of the HFL in macular disease
The Henle fiber layer (HFL) is comprised of bundles of unmyelinated photoreceptor axons
intermingled with outer Müller cell processes. The photoreceptor axons extend from the cell …
intermingled with outer Müller cell processes. The photoreceptor axons extend from the cell …
Photoreceptor cells and RPE contribute to the development of diabetic retinopathy
D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …
vascular disease, but work in the past years has shown abnormalities also in the neural …
Cellular signaling and factors involved in Müller cell gliosis: neuroprotective and detrimental effects
A Bringmann, I Iandiev, T Pannicke, A Wurm… - Progress in retinal and …, 2009 - Elsevier
Müller cells are active players in normal retinal function and in virtually all forms of retinal
injury and disease. Reactive Müller cells protect the tissue from further damage and …
injury and disease. Reactive Müller cells protect the tissue from further damage and …
Müller glial cells in retinal disease
A Bringmann, P Wiedemann - Ophthalmologica, 2011 - karger.com
Virtually all pathogenic stimuli activate Müller cells. Reactive Müller cells exert protective
and toxic effects on photoreceptors and neurons. They contribute to oxidative stress and …
and toxic effects on photoreceptors and neurons. They contribute to oxidative stress and …
Current concepts in the pathogenesis of age-related macular degeneration
MA Zarbin - Archives of ophthalmology, 2004 - jamanetwork.com
Objective To review and synthesize information concerning the pathogenesis ofage-related
macular degeneration (AMD). Methods Review of the English-language literature. Results …
macular degeneration (AMD). Methods Review of the English-language literature. Results …
Age-related macular degeneration
PTVM De Jong - New England Journal of Medicine, 2006 - Mass Medical Soc
Age-Related Macular Degeneration | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Diabetic retinopathy: seeing beyond glucose-induced microvascular disease
Diabetic retinopathy remains a frightening prospect to patients and frustrates physicians.
Destruction of damaged retina by photocoagulation remains the primary treatment nearly 50 …
Destruction of damaged retina by photocoagulation remains the primary treatment nearly 50 …
Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease
DY Yu, SJ Cringle - Progress in retinal and eye research, 2001 - Elsevier
Maintenance of an adequate oxygen supply to the retina is critical for retinal function. In
species with vascularised retinas, such as man, oxygen is delivered to the retina via a …
species with vascularised retinas, such as man, oxygen is delivered to the retina via a …
Oxidative damage and age-related macular degeneration
BS Winkler, ME Boulton, JD Gottsch… - Molecular …, 1999 - pmc.ncbi.nlm.nih.gov
This article provides current information on the potential role of oxidation in relation to age-
related macular degeneration (AMD). The emphasis is placed on the generation of oxidants …
related macular degeneration (AMD). The emphasis is placed on the generation of oxidants …