Sulfhydryl groups as targets of mercury toxicity

OP Ajsuvakova, AA Tinkov, M Aschner… - Coordination chemistry …, 2020 - Elsevier
The present study addresses existing data on the affinity and conjugation of sulfhydryl (thiol;-
SH) groups of low-and high-molecular-weight biological ligands with mercury (Hg). The …

Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury

M Farina, DS Avila, JBT Da Rocha… - Neurochemistry …, 2013 - Elsevier
Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …

Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies

M Farina, JBT Rocha, M Aschner - Life sciences, 2011 - Elsevier
Neurological disorders are common, costly, and can cause enduring disability. Although
mostly unknown, a few environmental toxicants are recognized causes of neurological …

Oxidative stress in MeHg-induced neurotoxicity

M Farina, M Aschner, JBT Rocha - Toxicology and applied pharmacology, 2011 - Elsevier
Methylmercury (MeHg) is an environmental toxicant that leads to long-lasting neurological
and developmental deficits in animals and humans. Although the molecular mechanisms …

[HTML][HTML] Methylmercury's chemistry: From the environment to the mammalian brain

PA Nogara, CS Oliveira, GL Schmitz, PC Piquini… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Methylmercury is a neurotoxicant that is found in fish and rice. MeHg's toxicity is mediated by
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …

The effect of environmental chemicals on the tumor microenvironment

SC Casey, M Vaccari, F Al-Mulla, R Al-Temaimi… - …, 2015 - academic.oup.com
Potentially carcinogenic compounds may cause cancer through direct DNA damage or
through indirect cellular or physiological effects. To study possible carcinogens, the fields of …

Electrodeposition of gold nanoparticles and reduced graphene oxide on an electrode for fast and sensitive determination of methylmercury in fish

Y Xu, W Zhang, J Shi, X Zou, Y Li, TH Elrasheid… - Food Chemistry, 2017 - Elsevier
Fish consumption is the main source of methylmercury (CH 3 Hg+) exposure for humans. In
this study, gold nanoparticles and reduced graphene oxide (AuNPs-RGO) modified …

[HTML][HTML] The effect of selected dental materials used in conservative dentistry, endodontics, surgery, and orthodontics as well as during the periodontal treatment on …

I Zieniewska, M Maciejczyk, A Zalewska - International Journal of …, 2020 - mdpi.com
Oxidative stress (OS) is a redox homeostasis disorder that results in oxidation of cell
components and thus disturbs cell metabolism. OS is induced by numerous internal as well …

[HTML][HTML] Risk assessment of oxidative stress induced by metal ions released from fixed orthodontic appliances during treatment and indications for supportive …

J Primožič, B Poljšak, P Jamnik, V Kovač… - Antioxidants, 2021 - mdpi.com
The treatment with fixed orthodontic appliances could have an important role in the induction
of oxidative stress and associated negative consequences. Because of the simultaneous …