Bridging barriers: advances and challenges in modeling biological barriers and measuring barrier integrity in organ-on-chip systems

A Ugodnikov, H Persson, CA Simmons - Lab on a Chip, 2024 - pubs.rsc.org
Biological barriers such as the blood–brain barrier, skin, and intestinal mucosal barrier play
key roles in homeostasis, disease physiology, and drug delivery–as such, it is important to …

A microfluidic platform with integrated porous membrane cell-substrate impedance spectroscopy (PM-ECIS) for biological barrier assessment

A Ugodnikov, J Lu, O Chebotarev, CA Simmons - bioRxiv, 2023 - biorxiv.org
Traditionally, biological barriers are assessed in vitro by measuring trans-
endothelial/epithelial electrical resistance (TEER) across a monolayer using handheld …

Monitoring Tissue Function Dynamics in vitro with Bioelectronics: Towards Understanding Barrett's Oesophagus Pathogenesis

DC Van Niekerk - 2024 - repository.cam.ac.uk
Barrett's oesophagus (BE) is a non-malignant, specialised intestinal metaplasia of the
oesophageal mucosa and a precursor of oesophageal adenocarcinoma (EAC). EAC is a …

Development and validation of platforms with integrated ECIS sensing for application to in vitro biological barrier modeling

A Ugodnikov - 2023 - search.proquest.com
Biological barriers, which separate body compartments and the external environment, play
key roles in homeostasis and protection of the body, through regulating nutrient transport …