Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment

S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

The wound microbiota: microbial mechanisms of impaired wound healing and infection

A Uberoi, A McCready-Vangi, EA Grice - Nature Reviews Microbiology, 2024 - nature.com
The skin barrier protects the human body from invasion by exogenous and pathogenic
microorganisms. A breach in this barrier exposes the underlying tissue to microbial …

Globally nitrogen addition alters soil microbial community structure, but has minor effects on soil microbial diversity and richness

X Wang, J Feng, G Ao, W Qin, M Han, Y Shen… - Soil Biology and …, 2023 - Elsevier
Globally increasing nitrogen (N) deposition is recognized as an important regulator of soil
microbial communities. However, how N enrichment affects soil microbial diversity, richness …

Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections

M Stracy, O Snitser, I Yelin, Y Amer, M Parizade, R Katz… - Science, 2022 - science.org
Treatment of bacterial infections currently focuses on choosing an antibiotic that matches a
pathogen's susceptibility, with less attention paid to the risk that even susceptibility-matched …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

Decreasing soil microbial diversity is associated with decreasing microbial biomass under nitrogen addition

C Wang, D Liu, E Bai - Soil Biology and Biochemistry, 2018 - Elsevier
While aboveground biodiversity has been widely studied, how microbial biodiversity
responds to increasing nitrogen (N) deposition is still unclear. Here we conducted a meta …

Biofilms in chronic wounds: pathogenesis and diagnosis

YK Wu, NC Cheng, CM Cheng - Trends in biotechnology, 2019 - cell.com
Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

M Malone, T Bjarnsholt, AJ McBain… - Journal of wound …, 2017 - magonlinelibrary.com
The presence of biofilms in chronic non-healing wounds, has been identified through in vitro
model and in vivo animal data. However, human chronic wound studies are under …

Biofilm-innate immune interface: contribution to chronic wound formation

Z Versey, WS da Cruz Nizer, E Russell, S Zigic… - Frontiers in …, 2021 - frontiersin.org
Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …