Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances

C Jia, Y Guo, FG Wu - Small, 2022 - Wiley Online Library
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …

Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Recent advances of cancer chemodynamic therapy based on Fenton/Fenton-like chemistry

C Cao, X Wang, N Yang, X Song, X Dong - Chemical science, 2022 - pubs.rsc.org
Applying Fenton chemistry in the tumor microenvironment (TME) for cancer therapy is the
most significant feature of chemodynamic therapy (CDT). Owing to the mild acid and …

Amplification of lipid peroxidation by regulating cell membrane unsaturation to enhance chemodynamic therapy

Y Zhu, P Gong, J Wang, J Cheng… - Angewandte Chemie …, 2023 - Wiley Online Library
Lipid peroxidation (LPO) is one of the most damaging processes in chemodynamic therapy
(CDT). Although it is well known that polyunsaturated fatty acids (PUFAs) are much more …

Recent advances in enhanced chemodynamic therapy strategies

Q Tian, F Xue, Y Wang, Y Cheng, L An, S Yang… - Nano Today, 2021 - Elsevier
Chemodynamic therapy (CDT) is a novel therapeutic modality that employs Fenton or
Fenton-like reactions to destroy cancer cells via the disproportionation of intratumoral …

Programmably controllable delivery of metastable ferrous ions for multiscale dynamic imaging guided photothermal primed chemodynamic therapy

X Zhang, S Lin, F Zhao, J Zhang, S Lei, F Bai… - Advanced …, 2023 - Wiley Online Library
Metallomodulation cell death strategies are extensively investigated for antitumor therapy,
such as cuproptosis, ferroptosis, and chemodynamic therapy (CDT). Undoubtedly, the …

Nanocatalyst‐mediated chemodynamic tumor therapy

L Zhang, CX Li, SS Wan… - Advanced healthcare …, 2022 - Wiley Online Library
Traditional tumor treatments, including chemotherapy, radiotherapy, photodynamic therapy,
and photothermal therapy, are developed and used to treat different types of cancer …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Strategies to engineer various nanocarrier-based hybrid catalysts for enhanced chemodynamic cancer therapy

JN Hao, K Ge, G Chen, B Dai, Y Li - Chemical Society Reviews, 2023 - pubs.rsc.org
Chemodynamic therapy (CDT) is a newly developed cancer-therapeutic modality that kills
cancer cells by the highly toxic hydroxyl radical (˙ OH) generated from the in situ triggered …

GSH/pH Dual Activatable Cross‐linked and Fluorinated PEI for Cancer Gene Therapy Through Endogenous Iron De‐Hijacking and in Situ ROS Amplification

S Yang, Y Wu, W Zhong, R Chen, M Wang… - Advanced …, 2024 - Wiley Online Library
Ferroptosis‐related cancer therapy is limited by insufficient Fe2+/Fe3+ redox pair and
hydrogen peroxide (H2O2) for producing lethal hydroxyl radicals (· OH). Although …