Circulating tumor cells (CTCs) are cancer cells that detach from the primary site and travel in
the blood stream. A higher number of CTCs increases the risk of breast cancer metastasis …

Breast cancer cells are suggested to be organized in a hierarchical manner with a
subpopulation of stem cells, termed as breast cancer stem cells (BCSCs), which contribute …

Crosstalk between inflammatory signalling pathways and receptor tyrosine kinases has
been revealed as an indicator of cancer malignant progression. In the present study, we …

Y-box binding protein 1 (YB-1) is a well-known oncogene highly expressed in various
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …

Understanding the pathological properties of dysregulated protein networks in individual
patients' tumors is the basis for precision therapy. Functional experiments are commonly …

Cancer types are commonly classified by histopathology and more recently through
molecular characteristics such as gene expression, mutations, copy number variations and …

Ribosomal S6 kinase (RSK) family is a group of serine/threonine kinases, including four
isoforms (RSK1/2/3/4). As a downstream effector of the Ras-mitogen-activated protein …

Medulloblastoma is the most common malignant brain tumor in children. This disease is
heterogeneous and is composed of four subtypes of medulloblastoma [WNT, Sonic …

Lung metastasis and relapse in osteosarcoma (OS) patients indicate poor prognosis. Here,
we identified significantly decreased expression of miR-382 in highly metastatic OS cell …

Two opposing clusters of transcription factors (TF) have been associated with the differential
risks of estrogen receptor positive or negative breast cancers, but the mechanisms …