PIC-king apart PRC1-mediated repression
Abstract Polycomb repressive complex 1 (PRC1) is an essential repressor of lineage-
specific genes central to the establishment and preservation of cellular identity. Recent …
specific genes central to the establishment and preservation of cellular identity. Recent …
DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
Mono-ubiquitination of lysine 18 on histone H3 (H3K18ub), catalyzed by UHRF1, is a
DNMT1 docking site that facilitates replication-coupled DNA methylation maintenance. Its …
DNMT1 docking site that facilitates replication-coupled DNA methylation maintenance. Its …
Histone deacetylase-1 is required for epigenome stability in Neurospora crassa
F Ebot-Ojong, AR Ferraro, F Kaddar, C Hull-Crew… - bioRxiv, 2025 - biorxiv.org
Polycomb group (PcG) proteins form chromatin modifying complexes that control cell fate,
mammalian X-chromosome inactivation, and plant vernalization. Polycomb Repressive …
mammalian X-chromosome inactivation, and plant vernalization. Polycomb Repressive …
The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation
The transition of embryonic stem cells (ESCs) from pluripotency to lineage commitment is
regulated by multiple mechanisms, including chromatin dynamics and both transcriptional …
regulated by multiple mechanisms, including chromatin dynamics and both transcriptional …
Targeted disruption of PRC1. 1 complex enhances bone remodeling
X Wu, D Liu, J Liu, S Feng, L **ng, J Xu, M Gong, Y Liu… - 2024 - researchsquare.com
Polycomb repressive complexes (PRCs) are pivotal epigenetic regulators preserving cell
identity by restricting the transcription responsiveness to sub-threshold levels of extracellular …
identity by restricting the transcription responsiveness to sub-threshold levels of extracellular …