Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects

S Kunjachan, J Ehling, G Storm, F Kiessling… - Chemical …, 2015 - ACS Publications
Nanomedicine is defined as “the application of nanotechnology to medicine, including the
use of nanometer-sized carrier materials for facilitating disease diagnosis, disease treatment …

Pathogenesis of Staphylococcus aureus Bloodstream Infections

L Thomer, O Schneewind… - Annual Review of …, 2016 - annualreviews.org
Staphylococcus aureus, a Gram-positive bacterium colonizing nares, skin, and the
gastrointestinal tract, frequently invades the skin, soft tissues, and bloodstreams of humans …

Delivery of antibiotics with polymeric particles

MH **ong, Y Bao, XZ Yang, YH Zhu, J Wang - Advanced drug delivery …, 2014 - Elsevier
Despite the wide use of antibiotics, bacterial infection is still one of the leading causes of
hospitalization and mortality. The clinical failure of antibiotic therapy is linked with low …

PET/MR imaging of inflammation in atherosclerosis

ML Senders, C Calcagno, A Tawakol… - Nature Biomedical …, 2023 - nature.com
Myocardial infarction, stroke, mental disorders, neurodegenerative processes, autoimmune
diseases, cancer and the human immunodeficiency virus impact the haematopoietic system …

Real-time in vivo imaging of invasive- and biomaterial-associated bacterial infections using fluorescently labelled vancomycin

M Van Oosten, T Schäfer, JAC Gazendam… - Nature …, 2013 - nature.com
Invasive and biomaterial-associated infections in humans are often difficult to diagnose and
treat. Here, guided by recent advances in clinically relevant optical imaging technologies …

Multifunctional nanoagents for ultrasensitive imaging and photoactive killing of Gram-negative and Gram-positive bacteria

J Tang, B Chu, J Wang, B Song, Y Su, H Wang… - Nature …, 2019 - nature.com
Simultaneous imaging and treatment of infections remains a major challenge, with most
current approaches being effective against only one specific group of bacteria or not being …

[HTML][HTML] Coagulation: At the heart of infective endocarditis

L Liesenborghs, S Meyers, T Vanassche… - Journal of Thrombosis …, 2020 - Elsevier
Infective endocarditis is a life‐threatening and enigmatic disease with a mortality of 30% and
a pathophysiology that is poorly understood. However, at its core, an endocarditis lesion is …

Nano-enabled sensing approaches for pathogenic bacterial detection

M Alafeef, P Moitra, D Pan - Biosensors and Bioelectronics, 2020 - Elsevier
Infectious diseases caused by pathogenic bacteria, especially antibiotic-resistant bacteria,
are one of the biggest threats to global health. To date, bacterial contamination is detected …

Synthetic biology: an emerging engineering discipline

AA Cheng, TK Lu - Annual review of biomedical engineering, 2012 - annualreviews.org
Over the past decade, synthetic biology has emerged as an engineering discipline for
biological systems. Compared with other substrates, biology poses a unique set of …