There are multiple diseases or conditions such as hereditary hemochromatosis, hemophilia,
thalassemia, sickle cell disease, aging, and estrogen deficiency that can cause iron …

Therapeutic advances in β‐thalassaemia have gradually lead to a significant improvement
in prognosis over the past few decades. As a result, patients living in areas where disease …

Conventional treatment of thalassemia, namely regular blood transfusion and iron chelation,
improves perspectives and quality of life; however, successful treatment leads to more time …

Beta-thalassemia is a heterogeneous group of anemic disorders caused by the absence or
defective production of beta-globin chains. Their clinical manifestations vary from …

Background: β-thalassemia heterozygotes produce sensitive levels of fetal hemoglobin and
hemoglobin A2 to remain asymptomatic for life compared to β-thalassemia intermedia and β …

Thalassemia is characterized by a defect in the synthesis of one or more of the globin
subunits of hemoglobin. This defect results in imbalance in the α/β-globin chain ratio …

Macrocephaly, characterized by an abnormally large head circumference, often co-occurs
with distinctive finger changes, presenting a diagnostic challenge for clinicians. This review …

Aim This review aims to overview factors contributing to TAO development and addresses
the targeted diagnostic work-up and treatment management in adult thalassemic patients …

Background Pain is a complication in patients with transfusion-dependent thalassemia
(TDT). There are several mechanisms underlying pain in people with thalassemia and low …

Background CMRtools is a software package that can be used to measure T2* values to
diagnose liver iron overload, however, its accuracy in terms is affected by multiple factors …