Non-coding RNAs and potential therapeutic targeting in cancer
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy
Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …
arising as important players in various biological pathways. They have received extensive …
The long noncoding RNA Malat1: Its physiological and pathophysiological functions
Recent studies suggest that in humans, DNA sequences responsible for protein coding
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …
Clinical utility of circulating non-coding RNAs—an update
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
[HTML][HTML] Genetics and molecular pathogenesis of gastric adenocarcinoma
Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of
cancer death. A complex disease arising from the interaction of environmental and host …
cancer death. A complex disease arising from the interaction of environmental and host …
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …
molecular biology assuming protein-coding genes as unique functional biological effectors …
MALAT1 Long Non-Coding RNA: Functional Implications
The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …
Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer
X Zhou, C Yin, Y Dang, F Ye, G Zhang - Scientific reports, 2015 - nature.com
Recent studies have demonstrated that long non-coding RNAs (lncRNAs) are regarded as
useful tools for cancer detection, particularly for the early stage; however, little is known …
useful tools for cancer detection, particularly for the early stage; however, little is known …
Non-coding RNAs as liquid biopsy biomarkers in cancer
Although non-coding RNAs have long been considered as non-functional “junk” RNAs,
accumulating evidence in the past decade indicates that they play a critical role in …
accumulating evidence in the past decade indicates that they play a critical role in …
Long noncoding RNA MALAT1 promotes hepatocellular carcinoma development by SRSF1 upregulation and mTOR activation
Several long noncoding RNAs (lncRNA) are abrogated in cancer but their precise
contributions to oncogenesis are still emerging. Here we report that the lncRNA MALAT1 is …
contributions to oncogenesis are still emerging. Here we report that the lncRNA MALAT1 is …