Alcohol readily crosses the placenta and may disrupt fetal development. Harm from prenatal
alcohol exposure (PAE) is determined by the dose, pattern, timing and duration of exposure …

One important challenge in psychiatric research is to translate findings from brain imaging
research studies that identified brain alterations in patient groups into an accurate diagnosis …

Cross-sectional studies have demonstrated strong associations between physical frailty and
depression. However, the evidence from prospective studies is limited. Here, we analyze …

Background Grip strength is a widely used and well-validated measure of overall health that
is increasingly understood to index risk for psychiatric illness and neurodegeneration in …

Background Neurocognitive deficits are common among youth with mental disorders, and
patterns of aberrant brain function generally cross diagnostic boundaries. This study …

PURPOSE Although abstinence is recommended in pregnancy, many pregnancies are
exposed to alcohol. Observational studies of the effects of low to moderate prenatal alcohol …

Prenatal alcohol exposure (PAE) affects neurodevelopment in over 59 million individuals
globally. Prior studies using dichotomous categorization of alcohol use and comorbid …

PURPOSE Alcohol and cannabis are the most commonly used substances during
adolescence and are typically initiated during this sensitive neurodevelopmental period. The …

Background Chronic liver diseases of all etiologies exist along a spectrum with varying
degrees of hepatic fibrosis. Despite accumulating evidence implying associations between …

Evidence is strong for adverse fetal effects of high level or chronic prenatal alcohol exposure
(PAE), but many pregnant women continue to drink at lower levels. The 'Asking Questions …