Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …

The basic organization of the catecholamine-containing neuronal systems and their axonal
projections in the brain was initially worked out using classical histofluorescence techniques …

Monoamine neurotransmitters such as dopamine and serotonin control important brain
pathways, including movement, sleep, reward and mood. Dysfunction of monoaminergic …

Monoamine neurotransmitters such as serotonin and dopamine are loaded by vesicular
monoamine transporter 2 (VMAT2) into synaptic vesicles for storage and subsequent …

Parkinson's disease (PD) coincides with a dramatic loss of dopaminergic neurons within the
substantia nigra. A key player in the loss of dopaminergic neurons is oxidative stress …

Abstract Vesicular monoamine transporter 2 (VMAT2) accumulates monoamines in
presynaptic vesicles for storage and exocytotic release, and has a vital role in …

A second isoform of the human vesicular monoamine transporter (hVMAT) has been cloned
from a pheochromocytoma cDNA library. The contribution of the two transporter isoforms to …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
elderly people and constitutes a major source of disability worldwide. Notably, the …

This book provides the reader with an account of some of the experimental evidence on
which our present knowledge is based. The third edition of this highly successful book has …

Many of the motoric features that define Parkinson disease (PD) result primarily from the loss
of the neuromelanin (NM)-containing dopamine (DA) neurons of the substantia nigra (SN) …