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Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective
EC Murray, R Nosalski, N MacRitchie… - Cardiovascular …, 2021 - academic.oup.com
Both animal models and human observational and genetic studies have shown that immune
and inflammatory mechanisms play a key role in hypertension and its complications. We …
and inflammatory mechanisms play a key role in hypertension and its complications. We …
Periodontitis and hypertension: is the association causal?
R Del Pinto, D Pietropaoli, E Munoz-Aguilera… - High Blood Pressure & …, 2020 - Springer
High blood pressure (BP) and periodontitis are two highly prevalent conditions worldwide
with a significant impact on cardiovascular disease (CVD) complications. Poor periodontal …
with a significant impact on cardiovascular disease (CVD) complications. Poor periodontal …
Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal …
M Czesnikiewicz-Guzik, G Osmenda… - European heart …, 2019 - academic.oup.com
Aims Inflammation is an important driver of hypertension. Periodontitis is a chronic
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …
Periodontitis, blood pressure, and the risk and control of arterial hypertension: epidemiological, clinical, and pathophysiological aspects—review of the literature and …
S Surma, M Romańczyk, J Witalińska-Łabuzek… - Current Hypertension …, 2021 - Springer
Abstract Purpose of Review Arterial hypertension is an important risk factor for
cardiovascular disease. In the world, about 45% of people suffer from arterial hypertension …
cardiovascular disease. In the world, about 45% of people suffer from arterial hypertension …
[HTML][HTML] Oral health as a modifiable risk factor for cardiovascular diseases
S Altamura, R Del Pinto, D Pietropaoli… - Trends in Cardiovascular …, 2023 - Elsevier
Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality worldwide
with a high socioeconomic burden. Increasing evidence supports a convincing connection …
with a high socioeconomic burden. Increasing evidence supports a convincing connection …
Association between oral health and cardiovascular outcomes in patients with hypertension: a nationwide cohort study
J Kim, HJ Kim, J Jeon, TJ Song - Journal of Hypertension, 2022 - journals.lww.com
Objective: Studies on the association of oral hygiene indicators with cardiovascular disease
in hypertensive patients have been lacking. Oral hygiene is directly or indirectly associated …
in hypertensive patients have been lacking. Oral hygiene is directly or indirectly associated …
[HTML][HTML] The effect of dietary nitrate on the oral microbiome and salivary biomarkers in individuals with high blood pressure
L du Toit, ML Sundqvist, A Redondo-Rio… - The Journal of …, 2024 - Elsevier
Background Green leafy vegetables (GLV) contain inorganic nitrate, an anion with potential
prebiotic effects on the oral microbiome. However, it remains unclear whether GLV and …
prebiotic effects on the oral microbiome. However, it remains unclear whether GLV and …
Inflammation-accelerated senescence and the cardiovascular system: mechanisms and perspectives
Low-grade chronic inflammation is a common denominator in atherogenesis and related
diseases. Solid evidence supports the occurrence of an impairment in the innate and …
diseases. Solid evidence supports the occurrence of an impairment in the innate and …
Is systemic inflammation a missing link between periodontitis and hypertension? Results from two large population‐based surveys
E Muñoz Aguilera, Y Leira… - Journal of Internal …, 2021 - Wiley Online Library
Objective The primary objective was to investigate the relationship between periodontitis
and hypertension in two independent large surveys. The secondary objective was to …
and hypertension in two independent large surveys. The secondary objective was to …
[HTML][HTML] Oral health and atherosclerotic cardiovascular disease: A review
E Gianos, EA Jackson, A Tejpal, K Aspry… - American journal of …, 2021 - Elsevier
Periodontal disease (PD) is common in the US and globally. Evidence suggests that poor
oral health is associated with atherosclerotic cardiovascular disease (ASCVD); however, this …
oral health is associated with atherosclerotic cardiovascular disease (ASCVD); however, this …