Current status of bacteriophage therapy for severe bacterial infections

T Sawa, K Moriyama, M Kinoshita - Journal of Intensive Care, 2024 - Springer
The increase in the incidence of antibiotic-resistant bacteria poses a global public health
threat. According to a 2019 WHO report, approximately 1.27 million deaths were attributed to …

Rapid and accurate testing for urinary tract infection: new clothes for the emperor

RB Moreland, L Brubaker, L Tinawi… - Clinical Microbiology …, 2024 - journals.asm.org
Urinary tract infection (UTI) is among the most common infections in clinical practice. In
some cases, if left untreated, it can lead to pyelonephritis and urosepsis. In other cases, UTI …

Bacterial single-cell RNA sequencing captures biofilm transcriptional heterogeneity and differential responses to immune pressure

LE Korshoj, T Kielian - Nature Communications, 2024 - nature.com
Biofilm formation is an important mechanism of survival and persistence for many bacterial
pathogens. These multicellular communities contain subpopulations of cells that display …

Global burden of antimicrobial resistance and forecasts to 2050

S Kariuki - The Lancet, 2024 - thelancet.com
The growing challenge of antimicrobial resistance (AMR) is now recognised as a global
public health emergency that requires concerted efforts by all stakeholders. 1 There is …

[HTML][HTML] Optimizing antibiotic use: Addressing resistance through effective strategies and health policies

M Capuozzo, A Zovi, R Langella, A Ottaiano… - Antibiotics, 2024 - mdpi.com
Background: Antimicrobial resistance (AMR) has emerged as a significant challenge to
public health, posing a considerable threat to effective disease management on a global …

Fate of fluoroquinolones associated with antimicrobial resistance in circular periurban agriculture

BP McCormick, CA Knecht, AC Sokolowski… - Science of the Total …, 2024 - Elsevier
Animal antibiotic use contributes to antimicrobial resistance (AMR) in humans. While animal
manure benefits soil fertility, it also acts as hotspot for antibiotic residues, antibiotic-resistant …

Predicting sepsis mortality into an era of pandrug-resistant E. coli through modeling

BJ Koch, DE Park, BA Hungate, CM Liu… - Communications …, 2024 - nature.com
Background Infections caused by antibiotic-resistant bacteria are increasingly frequent,
burdening healthcare systems worldwide. As pathogens acquire resistance to all known …

[HTML][HTML] Immune checkpoint blockade in experimental bacterial infections

NL Henriksen, PØ Jensen, LK Jensen - Journal of Infection, 2025 - Elsevier
Immune checkpoint inhibitors designed to reinvigorate immune responses suppressed by
cancer cells have revolutionized cancer therapy. Similarities in immune dysregulation …

[HTML][HTML] Black Phosphorus Nanoflakes: An Emerging Nanomaterial for Clinical Wound Management and Biomedical Applications

LS Smith, H Haidari, A Amsalu, GS Howarth… - International Journal of …, 2024 - mdpi.com
Black phosphorus (BP), a two-dimensional material, has gathered significant attention over
the last decade, primarily due to its unique physiochemical properties and potential role in …

The Antimicrobial Effects of Nitric Oxide: A Narrative Review

M Okda, S Spina, BS Fakhr, RW Carroll - Nitric Oxide, 2025 - Elsevier
Nitric oxide (NO) is a versatile endogenous molecule with multiple physiological roles,
including neurotransmission, vasodilation, and immune regulation. As part of the immune …