Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Understanding the role of the gut microbiome in gastrointestinal cancer: A review

D Ağagündüz, E Cocozza, Ö Cemali… - Frontiers in …, 2023 - frontiersin.org
Gastrointestinal cancer represents one of the most diagnosed types of cancer. Cancer is a
genetic and multifactorial disease, influenced by the host and environmental factors. It has …

Microbiome and cancer

N Cullin, CA Antunes, R Straussman… - Cancer cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Gut dysbiosis: Ecological causes and causative effects on human disease

SE Winter, AJ Bäumler - Proceedings of the National Academy of …, 2023 - pnas.org
The gut microbiota plays a role in many human diseases, but high-throughput sequence
analysis does not provide a straightforward path for defining healthy microbial communities …

The gut microbiota and inflammation: an overview

Z Al Bander, MD Nitert, A Mousa… - International journal of …, 2020 - mdpi.com
The gut microbiota encompasses a diverse community of bacteria that carry out various
functions influencing the overall health of the host. These comprise nutrient metabolism …

The global human gut microbiome: genes, lifestyles, and diet

M Parizadeh, MC Arrieta - Trends in Molecular Medicine, 2023 - cell.com
A growing number of human gut microbiome studies consistently describe differences
between human populations. Here, we review how factors related to host genetics, ethnicity …

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

SH Wong, J Yu - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …

The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in Cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Influence of the gut microbiome, diet, and environment on risk of colorectal cancer

M Song, AT Chan, J Sun - Gastroenterology, 2020 - Elsevier
Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity

X Long, CC Wong, L Tong, ESH Chu, C Ho Szeto… - Nature …, 2019 - nature.com
Emerging evidence implicates a role of the gut microbiota in colorectal cancer (CRC).
Peptostreptococcus anaerobius (P. anaerobius) is an anaerobic bacterium selectively …