Both the generation and the analysis of proteomics data are now widespread, and high-
throughput approaches are commonplace. Protocols continue to increase in complexity as …

Ensembl (http://www. ensembl. org/) is a bioinformatics project to organize biological
information around the sequences of large genomes. It is a comprehensive source of stable …

Abstract The BioMart Community Portal (www. biomart. org) is a community-driven effort to
provide a unified interface to biomedical databases that are distributed worldwide. The …

Genomic experiments produce multiple views of biological systems, among them are DNA
sequence and copy number variation, and mRNA and protein abundance. Understanding …

There is mounting evidence that seemingly diverse psychiatric disorders share genetic
etiology, but the biological substrates mediating this overlap are not well characterized. Here …

MicroRNAs (miRNAs) interact with target mRNAs at specific sites to induce cleavage of the
message or inhibit translation. The specific function of most mammalian miRNAs is …

biomaRt is a new Bioconductor package that integrates BioMart data resources with data
analysis software in Bioconductor. It can annotate a wide range of gene or gene product …

Abstract The International Cancer Genome Consortium (ICGC) is a collaborative effort to
characterize genomic abnormalities in 50 different cancer types. To make this data …

Abstract g: Profiler (http://biit. cs. ut. ee/gprofiler/) is a public web server for characterising
and manipulating gene lists resulting from mining high-throughput genomic data. g: Profiler …

High-throughput technologies have led to the rapid generation of large-scale datasets about
genes and gene products. These technologies have also shifted our research focus from …