Cigarette smoking and DNA methylation

KWK Lee, Z Pausova - Frontiers in genetics, 2013 - frontiersin.org
DNA methylation is the most studied epigenetic modification, capable of controlling gene
expression in the contexts of normal traits or diseases. It is highly dynamic during early …

Epigenetic regulation in development: is the mouse a good model for the human?

CW Hanna, H Demond, G Kelsey - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Over the past few years, advances in molecular technologies have allowed
unprecedented map** of epigenetic modifications in gametes and during early embryonic …

DNA methylation and recurrent pregnancy loss: a mysterious compass?

Q Zhou, Y **ong, B Qu, A Bao, Y Zhang - Frontiers in immunology, 2021 - frontiersin.org
Recurrent pregnancy loss (RPL) is a common and severe pathological pregnancy, whose
pathogenesis is not fully understood. With the development of epigenetics, the study of DNA …

Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke

SK Murphy, A Adigun, Z Huang, F Overcash, F Wang… - Gene, 2012 - Elsevier
Epigenetic alterations may mechanistically explain the developmental origins of adult
disease, namely the hypothesis that many complex adult chronic diseases originate as a …

DNA methylation defects in spermatozoa of male partners from couples experiencing recurrent pregnancy loss

K Khambata, S Raut, S Deshpande… - Human …, 2021 - academic.oup.com
STUDY QUESTION What is the sperm DNA methylation status of imprinted genes in male
partners from couples experiencing recurrent pregnancy loss (RPL)? SUMMARY ANSWER …

Methylation status of imprinted genes and repetitive elements in sperm DNA from infertile males

N El Hajj, U Zechner, E Schneider, A Tresch… - Sexual …, 2011 - karger.com
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide
epigenetic reprogramming processes during male germ-cell development may contribute to …

The human placental methylome

WP Robinson, EM Price - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
This review provides an overview of the unique features of DNA methylation in the human
placenta. We discuss the importance of understanding placental development, structure …

[HTML][HTML] Endocrine disruptors, environmental oxygen, epigenetics and pregnancy

JC Robins, CJ Marsit, JF Padbury… - Frontiers in bioscience …, 2011 - ncbi.nlm.nih.gov
The placenta and its myriad functions are central to successful reproductive outcomes.
These functions can be influenced by the environment encountered throughout pregnancy …

Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status

K King, S Murphy, C Hoyo - J Epidemiol Community Health, 2015 - jech.bmj.com
Background Children born to parents with lower income and education are at risk for obesity
and later-life risk of common chronic diseases, and epigenetics has been hypothesised to …

Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns

E Schneider, G Pliushch, N El Hajj… - Nucleic acids …, 2010 - academic.oup.com
DNA methylation is an epigenetic modification that plays an important role in gene
regulation. It can be influenced by stochastic events, environmental factors and …