Communication of gut microbiota and brain via immune and neuroendocrine signaling

K Kasarello, A Cudnoch-Jedrzejewska… - Frontiers in …, 2023 - frontiersin.org
The gastrointestinal tract of the human is inhabited by about 5× 1013 bacteria (of about
1,000 species) as well as archaea, fungi, and viruses. Gut microbiota is known to influence …

Neural circuits of interoception

GG Berntson, SS Khalsa - Trends in neurosciences, 2021 - cell.com
The present paper considers recent progress in our understanding of the afferent/ascending
neural pathways and neural circuits of interoception. Of particular note is the extensive role …

Gut microbiota changes require vagus nerve integrity to promote depressive-like behaviors in mice

E Siopi, M Galerne, M Rivagorda, S Saha… - Molecular …, 2023 - nature.com
Chronic stress constitutes a major risk factor for depression that can disrupt various aspects
of homeostasis, including the gut microbiome (GM). We have recently shown that GM …

[HTML][HTML] The vagus nerve at the interface of the microbiota-gut-brain axis

B Bonaz, T Bazin, S Pellissier - Frontiers in neuroscience, 2018 - frontiersin.org
The microbiota, the gut, and the brain communicate through the microbiota-gut-brain axis in
a bidirectional way that involves the autonomic nervous system. The vagus nerve (VN), the …

Microbiome–microglia connections via the gut–brain axis

R Abdel-Haq, JCM Schlachetzki, CK Glass… - Journal of Experimental …, 2019 - rupress.org
Microglia, the resident immune cells in the brain, are essential for modulating neurogenesis,
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …

The gut microbiome and mental health: advances in research and emerging priorities

AP Shoubridge, JM Choo, AM Martin, DJ Keating… - Molecular …, 2022 - nature.com
The gut microbiome exerts a considerable influence on human neurophysiology and mental
health. Interactions between intestinal microbiology and host regulatory systems have now …

Gut-brain psychology: rethinking psychology from the microbiota–gut–brain axis

S Liang, X Wu, F ** - Frontiers in integrative neuroscience, 2018 - frontiersin.org
Mental disorders and neurological diseases are becoming a rapidly increasing medical
burden. Although extensive studies have been conducted, the progress in develo** …

Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis

C Tan, Q Yan, Y Ma, J Fang, Y Yang - Frontiers in neurology, 2022 - frontiersin.org
Depression is a worldwide disease causing severe disability, morbidity, and mortality.
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …

[HTML][HTML] Gut microbiota in neurological diseases: Melatonin plays an important regulatory role

S Ahmadi, M Taghizadieh, E Mehdizadehfar… - Biomedicine & …, 2024 - Elsevier
Melatonin is a highly conserved molecule produced in the human pineal gland as a
hormone. It is known for its essential biological effects, such as antioxidant activity, circadian …

Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults

RT Liu, AD Rowan-Nash, AE Sheehan… - Brain, behavior, and …, 2020 - Elsevier
We assessed the gut microbiota of 90 American young adults, comparing 43 participants
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …