Thalamic subnetworks as units of function
The thalamus engages in various functions including sensory processing, attention, decision
making and memory. Classically, this diversity of function has been attributed to the nuclear …
making and memory. Classically, this diversity of function has been attributed to the nuclear …
Basal forebrain cholinergic signalling: development, connectivity and roles in cognition
Acetylcholine plays an essential role in fundamental aspects of cognition. Studies that have
mapped the activity and functional connectivity of cholinergic neurons have shown that the …
mapped the activity and functional connectivity of cholinergic neurons have shown that the …
[HTML][HTML] Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning
The amygdala is a brain region primarily associated with emotional response. The use of
genetic markers and single-cell transcriptomics can provide insights into behavior …
genetic markers and single-cell transcriptomics can provide insights into behavior …
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition
The amygdala processes positive and negative valence and contributes to addiction, but the
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas of …
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas of …
Cell-type profiling in salamanders identifies innovations in vertebrate forebrain evolution
J Woych, A Ortega Gurrola, A Deryckere, ECB Jaeger… - Science, 2022 - science.org
The evolution of advanced cognition in vertebrates is associated with two independent
innovations in the forebrain: the six-layered neocortex in mammals and the dorsal …
innovations in the forebrain: the six-layered neocortex in mammals and the dorsal …
[HTML][HTML] Vision-dependent specification of cell types and function in the develo** cortex
The role of postnatal experience in sculpting cortical circuitry, while long appreciated, is
poorly understood at the level of cell types. We explore this in the mouse primary visual …
poorly understood at the level of cell types. We explore this in the mouse primary visual …
Chromatin plasticity predetermines neuronal eligibility for memory trace formation
Memories are encoded by sparse populations of neurons but how such sparsity arises
remains largely unknown. We found that a neuron's eligibility to be recruited into the memory …
remains largely unknown. We found that a neuron's eligibility to be recruited into the memory …
[HTML][HTML] The complex role of inflammation and gliotransmitters in Parkinson's disease
Our understanding of the role of innate and adaptive immune cell function in brain health
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …
Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells
M Li, XK Yang, J Yang, TX Li, C Cui, X Peng, J Lei… - Neuron, 2024 - cell.com
Erasing traumatic memory during memory reconsolidation is a promising retrieval-extinction
strategy for post-traumatic stress disorder (PTSD). Here, we developed an acute social …
strategy for post-traumatic stress disorder (PTSD). Here, we developed an acute social …
Genetically-and spatially-defined basolateral amygdala neurons control food consumption and social interaction
The basolateral amygdala (BLA) contains discrete neuronal circuits that integrate positive or
negative emotional information and drive the appropriate innate and learned behaviors …
negative emotional information and drive the appropriate innate and learned behaviors …