Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

MSC based therapies—new perspectives for the injured lung

J Behnke, S Kremer, T Shahzad, CM Chao… - Journal of clinical …, 2020 - mdpi.com
Chronic lung diseases pose a tremendous global burden. At least one in four people suffer
from severe pulmonary sequelae over the course of a lifetime. Despite substantial …

The potential of mesenchymal stem cell therapy for chronic lung disease

FF Cruz, PRM Rocco - Expert Review of Respiratory Medicine, 2020 - Taylor & Francis
Introduction: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung
function and survival in chronic inflammatory lung diseases, including asthma, chronic …

Mesenchymal stem cells as a cornerstone in a galaxy of intercellular signals: basis for a new era of medicine

S Fernández-Francos, N Eiro, LA Costa… - International Journal of …, 2021 - mdpi.com
Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

A prospective, non-randomized, no placebo-controlled, phase Ib clinical trial to study the safety of the adipose derived stromal cells-stromal vascular fraction in …

A Tzouvelekis, V Paspaliaris, G Koliakos… - Journal of translational …, 2013 - Springer
Introduction Regenerative medicine and particular adult stem cells represent an alternative
option with several fruitful therapeutic applications in patients suffering from chronic lung …

[HTML][HTML] Mesenchymal stem cell-based therapy as an alternative to the treatment of acute respiratory distress syndrome: current evidence and future perspectives

S Fernández-Francos, N Eiro… - International journal of …, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) represents a current challenge for medicine
due to its incidence, morbidity and mortality and, also, the absence of an optimal treatment …

Chronic obstructive pulmonary disease and the cardiovascular system: vascular repair and regeneration as a therapeutic target

S Karnati, M Seimetz, F Kleefeldt… - Frontiers in …, 2021 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide and encompasses chronic bronchitis and emphysema. It has been shown that …

Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?

W Broekman, PPSJ Khedoe, K Schepers, H Roelofs… - Thorax, 2018 - thorax.bmj.com
COPD is characterised by tissue destruction and inflammation. Given the lack of curative
treatments and the progressive nature of the disease, new treatments for COPD are highly …

Cell therapy in patients with COVID-19 using Wharton's jelly mesenchymal stem cells: a phase 1 clinical trial

M Saleh, AA Vaezi, R Aliannejad… - Stem cell research & …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have received particular attention
because of their ability to modulate the immune system and inhibit inflammation caused by …

[HTML][HTML] Long-acting inhaled medicines: Present and future

C Zhang, D D'Angelo, F Buttini, M Yang - Advanced drug delivery reviews, 2024 - Elsevier
Inhaled medicines continue to be an essential part of treatment for respiratory diseases such
as asthma, chronic obstructive pulmonary disease, and cystic fibrosis. In addition, inhalation …