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Aquaporins: important but elusive drug targets
AS Verkman, MO Anderson… - Nature reviews Drug …, 2014 - nature.com
The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water
transport across the plasma membranes of cells in response to osmotic gradients. Data from …
transport across the plasma membranes of cells in response to osmotic gradients. Data from …
Chloroplast function and ion regulation in plants growing on saline soils: lessons from halophytes
Salt stress impacts multiple aspects of plant metabolism and physiology. For instance it
inhibits photosynthesis through stomatal limitation, causes excessive accumulation of …
inhibits photosynthesis through stomatal limitation, causes excessive accumulation of …
Plant aquaporins: membrane channels with multiple integrated functions
C Maurel, L Verdoucq, DT Luu… - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Aquaporins are channel proteins present in the plasma and intracellular membranes of plant
cells, where they facilitate the transport of water and/or small neutral solutes (urea, boric …
cells, where they facilitate the transport of water and/or small neutral solutes (urea, boric …
Ammonia production, excretion, toxicity, and defense in fish: a review
Many fishes are ammonotelic but some species can detoxify ammonia to glutamine or urea.
Certain fish species can accumulate high levels of ammonia in the brain or defense against …
Certain fish species can accumulate high levels of ammonia in the brain or defense against …
Ectomycorrhizas and water relations of trees: a review
T Lehto, JJ Zwiazek - Mycorrhiza, 2011 - Springer
There is plenty of evidence for improved nutrient acquisition by ectomycorrhizas in trees;
however, their role in water uptake is much less clear. In addition to experiments showing …
however, their role in water uptake is much less clear. In addition to experiments showing …
Plant aquaporins: roles in plant physiology
Background Aquaporins are membrane channels that facilitate the transport of water and
small neutral molecules across biological membranes of most living organisms. Scope of …
small neutral molecules across biological membranes of most living organisms. Scope of …
Ammonia toxicity to the brain
Hyperammonemia can be caused by various acquired or inherited disorders such as urea
cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in …
cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in …
Multiple functions of the crustacean gill: osmotic/ionic regulation, acid-base balance, ammonia excretion, and bioaccumulation of toxic metals
The crustacean gill is a multi-functional organ, and it is the site of a number of physiological
processes, including ion transport, which is the basis for hemolymph osmoregulation; acid …
processes, including ion transport, which is the basis for hemolymph osmoregulation; acid …
Ammonium stress in Arabidopsis: signaling, genetic loci, and physiological targets
Ammonium (NH 4+) toxicity is a significant ecological and agricultural issue, and an
important phenomenon in cell biology. As a result of increasing soil nitrogen input and …
important phenomenon in cell biology. As a result of increasing soil nitrogen input and …
Non‐selective cation channel activity of aquaporin AtPIP2;1 regulated by Ca2+ and pH
The aquaporin AtPIP2; 1 is an abundant plasma membrane intrinsic protein in Arabidopsis
thaliana that is implicated in stomatal closure, and is highly expressed in plasma …
thaliana that is implicated in stomatal closure, and is highly expressed in plasma …