Phase transitions of associative biomacromolecules
Multivalent proteins and nucleic acids, collectively referred to as multivalent associative
biomacromolecules, provide the driving forces for the formation and compositional …
biomacromolecules, provide the driving forces for the formation and compositional …
Direct prediction of intrinsically disordered protein conformational properties from sequence
Intrinsically disordered regions (IDRs) are ubiquitous across all domains of life and play a
range of functional roles. While folded domains are generally well-described by a stable 3D …
range of functional roles. While folded domains are generally well-described by a stable 3D …
Dynamical control enables the formation of demixed biomolecular condensates
Cellular matter can be organized into compositionally distinct biomolecular condensates.
For example, in Ashbya gossypii, the RNA-binding protein Whi3 forms distinct condensates …
For example, in Ashbya gossypii, the RNA-binding protein Whi3 forms distinct condensates …
Approaches to characterize chromatin subcompartment organization in the cell nucleus
The mechanism of self-organization of chromatin subcompartments on the 0.1–1 μm scale
and their impact on genome-associated activities has long been a key aspect of research on …
and their impact on genome-associated activities has long been a key aspect of research on …
[HTML][HTML] Cytochrome c prompts the recruitment of its nuclear partners SET/TAF-Iβ and NPM1 into biomolecular condensates
MÁ Casado-Combreras, A Velázquez-Campoy… - Iscience, 2024 - cell.com
Compartmentalization of proteins by liquid-liquid phase separation (LLPS) is used by cells
to control biochemical reactions spatially and temporally. Among them, the recruitment of …
to control biochemical reactions spatially and temporally. Among them, the recruitment of …
[HTML][HTML] Exploring the potential of TENO and WENO schemes for simulating under-resolved turbulent flows in the atmosphere using Euler equations
This paper focuses on the design and analysis of very high-order finite volume methods for
the computation of simplified meso-and micro-scale atmospheric flows. In a dry atmosphere …
the computation of simplified meso-and micro-scale atmospheric flows. In a dry atmosphere …
Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates
Nucleoli are surrounded by pericentromeric heterochromatin (PCH), reflecting a close
spatial association between the two largest biomolecular condensates in eukaryotic nuclei …
spatial association between the two largest biomolecular condensates in eukaryotic nuclei …
Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
Proteins containing prion-like low complexity domains (PLDs) are common drivers of the
formation of biomolecular condensates and are prone to misregulation due to amino acid …
formation of biomolecular condensates and are prone to misregulation due to amino acid …
Universal predictive scaling laws for phase separation of prion-like low complexity domains
J Joseph, MJ Maristany, AA Gonzalez… - 2023 - researchsquare.com
Proteins containing prion-like low complexity domains (PLDs) are common drivers of the
formation of biomolecular condensates and are prone to misregulation due to amino acid …
formation of biomolecular condensates and are prone to misregulation due to amino acid …
[PDF][PDF] Cytochrome c prompts the recruitment of its nuclear partners SET/TAF-Ib and NPM1 into biomolecular condensates
A Combreras, M Campoy, V Martinho, MAD Belle… - zaguan.unizar.es
Compartmentalization of proteins by liquid-liquid phase separation (LLPS) is used by cells
to control biochemical reactions spatially and temporally. Among them, the recruitment of …
to control biochemical reactions spatially and temporally. Among them, the recruitment of …