[HTML][HTML] Buccal films: A review of therapeutic opportunities, formulations & relevant evaluation approaches

L Shipp, F Liu, L Kerai-Varsani, TC Okwuosa - Journal of Controlled …, 2022 - Elsevier
The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …

An updated overview of the emerging role of patch and film-based buccal delivery systems

S Jacob, AB Nair, SHS Boddu, B Gorain, N Sreeharsha… - Pharmaceutics, 2021 - mdpi.com
Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …

3D printing of a wearable personalized oral delivery device: A first-in-human study

K Liang, S Carmone, D Brambilla, JC Leroux - Science advances, 2018 - science.org
Despite the burgeoning interest in three-dimensional (3D) printing for the manufacture of
customizable oral dosage formulations, a US Food and Drug Administration–approved …

Spray dried powders for nasal delivery: Process and formulation considerations

P Henriques, A Fortuna, S Doktorovová - European Journal of …, 2022 - Elsevier
Powders for nasal delivery have been recognized as advantageous dosage forms over
liquids due to increased stability and residence time on nasal mucosa, with improved …

The Why, Where, Who, How, and What of the vesicular delivery systems

B Kapoor, R Gupta, M Gulati, SK Singh… - Advances in colloid and …, 2019 - Elsevier
Though vesicular delivery systems have been widely explored and reviewed, no
comprehensive review exists that covers their development from the inception of the concept …

Development of mucoadhesive buccal film for rizatriptan: In vitro and in vivo evaluation

AB Nair, J Shah, S Jacob, BE Al-Dhubiab, V Patel… - Pharmaceutics, 2021 - mdpi.com
The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low
oral bioavailability and extensive first pass metabolism. The purpose of this investigation …

Functional ibuprofen-loaded cationic nanoemulsion: Development and optimization for dry eye disease treatment

BJ Dukovski, M Juretić, D Bračko, D Randjelović… - International Journal of …, 2020 - Elsevier
Inflammation plays a key role in dry eye disease (DED) affecting millions of people
worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) can be used topically to act on …

Chitosan for biomedical applications, promising antidiabetic drug delivery system, and new diabetes mellitus treatment based on stem cell

SI Othman, AM Alturki, GM Abu-Taweel… - International Journal of …, 2021 - Elsevier
Since chitosan's excellent pharmacokinetic and chemical properties, it is an attractive and
promising carbohydrate biopolymer in biomedical applications. Chitosan's beneficial …

Design, fabrication and characterisation of drug-loaded vaginal films: State-of-the-art

F Notario-Pérez, R Cazorla-Luna, A Martín-Illana… - Journal of Controlled …, 2020 - Elsevier
Films have undoubtedly seen the most significant advances in their development in recent
years of all the pharmaceutical forms for the vaginal administration of drugs. Films combine …

Electrospun metronidazole-loaded nanofibers for vaginal drug delivery

F Tuğcu-Demiröz, S Saar, S Tort… - Drug development and …, 2020 - Taylor & Francis
Objective: To develop and characterize innovative vaginal dosage forms for the treatment of
bacterial vaginosis (BV). Significance: This study is the first comparative evaluation of the …