Monoclonal antibodies (mAbs) are subject to instability issues linked to their protein nature.
In this work, we review the different mechanisms that can be linked to monoclonal antibodies …

There is considerable interest in the pharmaceutical industry toward development of
antibody-based biotherapeutics because they can selectively bind diverse receptors and …

Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

The growing need for biologics to be administered subcutaneously and ocularly, coupled
with certain indications requiring high doses, has resulted in an increase in drug substance …

Early identification of antibody candidates with drug-like properties is essential for
simplifying the development of safe and effective antibody therapeutics. For subcutaneous …

Protein pharmaceuticals have become a significant class of marketed drug products and are
expected to grow steadily over the next decade. Development of a commercial protein …

Three critical aspects that define high concentration antibody products (HCAPs) are as
follows: 1) formulation composition, 2) dosage form, and 3) primary packaging configuration …

Monoclonal antibodies (mAbs) have revolutionised the biopharmaceutical market. Being
proteinaceous, mAbs are prone to chemical and physical instabilities. Various approaches …

Plasmonic coupling via nanoparticle assembly is a popular signal-generation method in
bioanalytical sensors. Here, we customized an all-peptide-based ligand that carries an …

Administration of monoclonal antibodies (mAbs) is currently focused on subcutaneous
injection associated with increased patient adherence and reduced treatment cost, leading …