Mass spectrometry analysis of drugs of abuse: challenges and emerging strategies

SA Borden, J Palaty, V Termopoli… - Mass spectrometry …, 2020 - Wiley Online Library
Mass spectrometry has been the “gold standard” for drugs of abuse (DoA) analysis for many
decades because of the selectivity and sensitivity it affords. Recent progress in all aspects of …

High-performance liquid chromatography combined with electron ionization mass spectrometry: A review

F Rigano, PQ Tranchida, P Dugo, L Mondello - TrAC Trends in Analytical …, 2019 - Elsevier
The present review illustrates the state of the art in the field of liquid chromatography (LC)
hyphenated to electron ionization mass spectrometry (EI MS). An overview of applications …

Is nontarget screening of emerging contaminants by LC-HRMS successful? A plea for compound libraries and computer tools

M Zedda, C Zwiener - Analytical and bioanalytical chemistry, 2012 - Springer
This review focuses on the possibilities and limits of nontarget screening of emerging
contaminants, with emphasis on recent applications and developments in data evaluation …

Evaluation of a liquid electron ionization liquid chromatography–mass spectrometry interface

V Termopoli, G Famiglini, P Palma… - … of Chromatography A, 2019 - Elsevier
Abstract Liquid Electron Ionization (LEI), is an innovative liquid chromatography-mass
spectrometry (LC–MS) interface that converts liquid HPLC eluent to the gas-phase in a mass …

NanoLC-EI-MS: Perspectives in Biochemical Analysis

NG Pereira dos Santos, EVS Maciel… - International Journal of …, 2023 - mdpi.com
Although LC-MS with atmospheric pressure ionization (API) sources is the primary
technique used in modern bioanalytical studies, electron ionization mass spectrometry (EI …

Pharmacokinetic study of cinnamaldehyde in rats by GC–MS after oral and intravenous administration

H Zhao, Y **e, Q Yang, Y Cao, H Tu, W Cao… - … of pharmaceutical and …, 2014 - Elsevier
A selective and sensitive method utilizing gas chromatography–mass spectrometry was
developed for simultaneous determination of cinnamaldehyde, cinnamyl alcohol, and methyl …

Atmospheric pressure vaporization mechanism for coupling a liquid phase with electron ionization mass spectrometry

V Termopoli, G Famiglini, P Palma… - Analytical …, 2017 - ACS Publications
A novel liquid chromatography–mass spectrometry (LC–MS) interfacing concept is
presented and discussed. The new interface, called liquid-EI (LEI), is based on electron …

Three-dimensional chemical imaging of skin using stimulated Raman scattering microscopy

DM Drutis, TM Hancewicz… - Journal of …, 2014 - spiedigitallibrary.org
Stimulated Raman scattering (SRS) microscopy is used to generate structural and chemical
three-dimensional images of native skin. We employed SRS microscopy to investigate the …

Combining linear retention index and electron ionization mass spectrometry for a reliable identification in nano liquid chromatography

F Rigano, M Russo, A Arigò, P Dugo… - … of Chromatography A, 2020 - Elsevier
The present research is focused on the object to improve identification capability in liquid
chromatography (LC), by creating a system as similar as possible to gas chromatography …

The overshadowed role of electron ionization–mass spectrometry in analytical biotechnology

DAV Medina, EVS Maciel, NGP Dos Santos… - Current Opinion in …, 2023 - Elsevier
Highlights•EI-MS offers unparalleled molecule identification capabilities.•The matrix-effect-
free nature of EI-MS is peerless for biotechnology analysis.•EI-MS bridges the gap between …