Neurodegenerative diseases are a major public health problem worldwide with a wide
spectrum of symptoms and physiological effects. It has been long reported that the …

Lycopene is an aliphatic hydrocarbon carotenoid extracted from plants like tomatoes,
papayas, and watermelons. Previous studies have shown that lycopene can exert …

Background Cognitive decline occurs frequently in Parkinson's disease (PD), which greatly
decreases the quality of life of patients. However, the mechanisms remain to be investigated …

Iron accumulation and neuroinflammation are pathological conditions found in several
neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease …

Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders which is characterised neuropathologically by progressive loss of dopaminergic …

Parkinson's disease (PD) is a complex, multisystem disorder characterised by α-synuclein
(SNCA) pathology, degeneration of nigrostriatal dopaminergic neurons, multifactorial …

Adrenergic systems regulate both cognitive function and immune function. The primary
source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus …

Degeneration of the noradrenergic system is now considered a pathological hallmark of
Parkinson's disease, but little is known about its consequences in terms of parkinsonian …

Apart from dopaminergic neurotoxicity, exposure to rotenone, a commonly used insecticide
in agriculture, also adversely affects hippocampal and cortical neurons, resulting in cognitive …

Background Sepsis-associated acute brain inflammation, if unresolved, may cause chronic
neuroinflammation and resultant neurodegenerative diseases. However, little is known how …