International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Rhinitis associated with asthma is distinct from rhinitis alone: the ARIA‐MeDALL hypothesis

J Bousquet, E Melén, T Haahtela, GH Koppelman… - Allergy, 2023 - Wiley Online Library
Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

[HTML][HTML] “Air That Once Was Breath” Part 1: Wildfire-Smoke-Induced Mechanisms of Airway Inflammation–“Climate Change, Allergy and Immunology” Special IAAI …

WS Bowman, RJ Schmidt, GK Sanghar… - … Archives of Allergy and …, 2024 - karger.com
Background: Wildfires are a global concern due to their wide-ranging environmental,
economic, and public health impacts. Climate change contributes to an increase in the …

Recent progress in the genetic and epigenetic underpinnings of atopy

CH Baloh, RA Mathias - Journal of Allergy and Clinical Immunology, 2023 - Elsevier
In the past 2 years, there continue to be advances in our understanding of the genetic and
epigenetic underpinnings of atopy pertaining to disease risk and disease severity. The joint …

Epigenome-wide association studies of allergic disease and the environment

A Cardenas, RP Fadadu, GH Koppelman - Journal of Allergy and Clinical …, 2023 - Elsevier
The epigenome is at the intersection of the environment, genotype, and cellular response.
DNA methylation of cytosine nucleotides, the most studied epigenetic modification, has been …

DNA methylation biomarkers in asthma and rhinitis: are we there yet?

E Legaki, C Arsenis, S Taka… - Clinical and …, 2022 - Wiley Online Library
The study of epigenetics has improved our understanding of mechanisms underpinning
gene‐environment interactions and is providing new insights in the pathophysiology of …

Epigenetic regulation of pulmonary inflammation

S Ahmad, XL Zhang, A Ahmad - Seminars in cell & developmental biology, 2024 - Elsevier
Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …

The role of DNA methylation in personalized medicine for immune-related diseases

MK Gupta, H Peng, Y Li, CJ Xu - Pharmacology & Therapeutics, 2023 - Elsevier
Epigenetics functions as a bridge between host genetic & environmental factors, aiding in
human health and diseases. Many immune-related diseases, including infectious and …

Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma

K Recto, P Kachroo, T Huan, D Van Den Berg… - …, 2023 - thelancet.com
Background Identifying novel epigenetic signatures associated with serum immunoglobulin
E (IgE) may improve our understanding of molecular mechanisms underlying asthma and …