Cognitive deficits are a core aspect of psychotic disorders; however, it is not clear to which
extent different pharmacological treatments could distinctly impact these outcomes. Hence …

These updated guidelines are based on a first edition of the World Federation of Societies of
Biological Psychiatry Guidelines for Biological Treatment of Schizophrenia published in …

Context Neurocognitive impairment in schizophrenia is severe and is an important predictor
of functional outcome. The relative effect of the second-generation (atypical) antipsychotic …

Cognitive dysfunction is a core feature of schizophrenia. Deficits are moderate to severe
across several domains, including attention, working memory, verbal learning and memory …

Cognitive functioning is moderately to severely impaired in patients with schizophrenia. This
impairment is the prime driver of the significant disabilities in occupational, social, and …

Prefrontal cortical executive functions comprise a number of cognitive capabilities necessary
for goal directed behavior and adaptation to a changing environment. Executive dysfunction …

Objective: Cognitive impairment, manifested as mild to moderate deviations from
psychometric norms, is present in many but not all schizophrenia patients. The purpose of …

Context Cognitive impairment in schizophrenia is frequent, involves multiple domains, and is
enduring. Numerous recent clinical trials have suggested that second-generation …

Cognitive deficits in schizophrenia are among the core symptoms of the disease, correlate
with functional outcome, and are not well treated with current antipsychotic therapies. In …

Generalized cognitive impairments are stable deficits linked to schizophrenia and key
factors associated with functional disability in the disorder. Preclinical data suggest that …