Mesoporous silica materials: From physico-chemical properties to enhanced dissolution of poorly water-soluble drugs

A Maleki, H Kettiger, A Schoubben… - Journal of Controlled …, 2017 - Elsevier
New approaches in pharmaceutical chemistry have resulted in more complex drug
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …

Solid-state nuclear magnetic resonance investigations of the nature, property, and activity of acid sites on solid catalysts

Y Jiang, J Huang, W Dai, M Hunger - Solid state nuclear magnetic …, 2011 - Elsevier
Further progress in the field of heterogeneous catalysis depends on our knowledge of the
nature and behavior of surface sites on solid catalysts and of the mechanisms of chemical …

Elucidating the bimodal acid− base behavior of the water− silica interface from first principles

K Leung, IMB Nielsen, LJ Criscenti - Journal of the American …, 2009 - ACS Publications
Understanding the acid− base behavior of silica surfaces is critical for many nanoscience
and bionano interface applications. Silanol groups (SiOH) on silica surfaces exhibit two …

Size-controlled functionalized mesoporous silica nanoparticles for tunable drug release and enhanced anti-tumoral activity

M Bouchoucha, MF Côté, R C.-Gaudreault… - Chemistry of …, 2016 - ACS Publications
Mesoporous silica nanoparticles (MSNs) are considered as one of the most promising
nanovectors for controlled drug delivery. For the design of ideal drug nanocarriers, several …

Dissolution kinetics of mesoporous silica nanoparticles in different simulated body fluids

K Braun, A Pochert, M Beck, R Fiedler, J Gruber… - Journal of Sol-Gel …, 2016 - Springer
The application of mesoporous silica nanoparticles as a platform for drug delivery and
bioimaging requires a good understanding of the degradability of these particles under …

Towards establishing structure–activity relationships for mesoporous silica in drug delivery applications

JM Rosenholm, M Lindén - Journal of controlled release, 2008 - Elsevier
Mesoporous silicas are currently widely studied carrier matrices in drug delivery
applications. Surface functionalization of the silica is often employed in order to enhance the …

Recyclable organocatalysts based on hybrid silicas

M Ferré, R Pleixats, MWC Man, X Cattoën - Green chemistry, 2016 - pubs.rsc.org
The quest for efficient and “greener” catalysts for chemical processes has set a precedent for
the development of reliable methods for their synthesis. These methods, based on …

Aqueous bromate reduction by catalytic hydrogenation over Pd/Al2O3 catalysts

H Chen, Z Xu, H Wan, J Zheng, D Yin… - Applied Catalysis B …, 2010 - Elsevier
Bromate is recognized as an oxyhalide disinfection byproduct in drinking water. In this study,
supported noble metal (Pd, Pt) catalysts with different supports of SiO2, Al2O3 and activated …

Wet-chemical analysis of surface concentration of accessible groups on different amino-functionalized mesoporous SBA-15 silicas

JM Rosenholm, M Lindén - Chemistry of Materials, 2007 - ACS Publications
Surface functionalization is one of the key steps toward the utilization of mesoporous
materials in different applications. In this study, we characterized amino-functionalized …

Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10

AK Meka, A Gopalakrishna, C Iriarte-Mesa… - Molecular …, 2023 - ACS Publications
Coenzyme Q10 is a potent antioxidant that plays an important role in the maintenance of
various biochemical pathways of the body and has a wide range of therapeutic applications …