[HTML][HTML] Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty
The mechanisms leading to a predominantly hypertrophied phenotype versus a
predominantly oxidative phenotype, the hallmarks of resistance training (RT) or aerobic …
predominantly oxidative phenotype, the hallmarks of resistance training (RT) or aerobic …
Maintaining proteostasis under mechanical stress
Cell survival, tissue integrity and organismal health depend on the ability to maintain
functional protein networks even under conditions that threaten protein integrity. Protection …
functional protein networks even under conditions that threaten protein integrity. Protection …
Filamin C in cardiomyopathy: from physiological roles to DNA variants
S Song, A Shi, H Lian, S Hu, Y Nie - Heart Failure Reviews, 2022 - Springer
Cardiomyopathy affects approximately 1 in 500 adults and is the leading cause of death.
Familial cases are common, and mutations in many genes are involved in cardiomyopathy …
Familial cases are common, and mutations in many genes are involved in cardiomyopathy …
Mimicking exercise in vitro: effects of myotube contractions and mechanical stretch on omics
The number of studies using skeletal muscle (SkM) cell culture models to study exercise in
vitro are rapidly expanding. Progressively, more comprehensive analysis methods, such as …
vitro are rapidly expanding. Progressively, more comprehensive analysis methods, such as …
Protein phosphatase-1 regulates the binding of filamin C to FILIP1 in cultured skeletal muscle cells under mechanical stress
T Kokot, JP Zimmermann, AN Schwäble, L Reimann… - Scientific Reports, 2024 - nature.com
The actin-binding protein filamin c (FLNc) is a key mediator in the response of skeletal
muscle cells to mechanical stress. In addition to its function as a structural scaffold, FLNc …
muscle cells to mechanical stress. In addition to its function as a structural scaffold, FLNc …
Post-natal muscle growth and protein turnover: a narrative review of current understanding
DJ Millward - Nutrition research reviews, 2023 - cambridge.org
A model explaining the dietary-protein driven post-natal skeletal muscle growth and protein
turnover in the rat is updated, and the mechanisms involved described in this narrative …
turnover in the rat is updated, and the mechanisms involved described in this narrative …
GePI: large-scale text mining, customized retrieval and flexible filtering of gene/protein interactions
We present GePI, a novel Web server for large-scale text mining of molecular interactions
from the scientific biomedical literature. GePI leverages natural language processing …
from the scientific biomedical literature. GePI leverages natural language processing …
Phosphoproteomics profiling defines a target landscape of the basophilic protein kinases AKT, S6K, and RSK in skeletal myotubes
AL Fricke, WWD Mühlhäuser… - Journal of Proteome …, 2023 - ACS Publications
Phosphorylation-dependent signal transduction plays an important role in regulating the
functions and fate of skeletal muscle cells. Central players in the phospho-signaling network …
functions and fate of skeletal muscle cells. Central players in the phospho-signaling network …
Identification of copy number variations in the genome of Dairy Gir cattle
Studying structural variants that can control complex traits is relevant for dairy cattle
production, especially for animals that are tolerant to breeding conditions in the tropics, such …
production, especially for animals that are tolerant to breeding conditions in the tropics, such …
Dynamic changes to the skeletal muscle proteome and ubiquitinome induced by the E3 ligase, ASB2β
Ubiquitination is a posttranslational protein modification that has been shown to have a
range of effects, including regulation of protein function, interaction, localization, and …
range of effects, including regulation of protein function, interaction, localization, and …