[HTML][HTML] Blood–brain barrier dynamics to maintain brain homeostasis
M Segarra, MR Aburto, A Acker-Palmer - Trends in neurosciences, 2021 - cell.com
The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …
The CLDN5 gene at the blood-brain barrier in health and disease
The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
C Greene, R Connolly, D Brennan, A Laffan… - Nature …, 2024 - nature.com
Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19)
pathogenesis and may predispose to the neurological sequelae associated with long …
pathogenesis and may predispose to the neurological sequelae associated with long …
Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue
Prevalence, symptoms, and treatment of depression suggest that major depressive
disorders (MDD) present sex differences. Social stress-induced neurovascular pathology is …
disorders (MDD) present sex differences. Social stress-induced neurovascular pathology is …
Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis
Elevations in peripheral inflammatory markers have been reported in patients with
psychosis. Whether this represents an inflammatory process defined by individual or …
psychosis. Whether this represents an inflammatory process defined by individual or …
Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disorders
Major psychiatric disorders affect 25% of the population. While genetic and environmental
risk factors have been identified, the underlying pathophysiology of conditions, such as …
risk factors have been identified, the underlying pathophysiology of conditions, such as …
[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …
Inflammation‐driven brain and gut barrier dysfunction in stress and mood disorders
Regulation of emotions is generally associated exclusively with the brain. However, there is
evidence that peripheral systems are also involved in mood, stress vulnerability vs …
evidence that peripheral systems are also involved in mood, stress vulnerability vs …
Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders
Although there is convergent evidence for blood-brain barrier (BBB) dysfunction and
peripheral inflammation in schizophrenia (SZ) and bipolar disorder (BD), it is unknown …
peripheral inflammation in schizophrenia (SZ) and bipolar disorder (BD), it is unknown …
[HTML][HTML] Neurovascular adaptations modulating cognition, mood, and stress responses
The neurovascular unit (NVU) is a dynamic center for substance exchange between the
blood and the brain, making it an essential gatekeeper for central nervous system (CNS) …
blood and the brain, making it an essential gatekeeper for central nervous system (CNS) …