With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …

According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

The geroscience hypothesis proposes that therapy to slow or reverse molecular changes
that occur with aging can delay or prevent multiple chronic diseases and extend healthy …

Slower epigenetic aging is associated with exposure to green space (greenness); however,
the longitudinal relationship has not been well studied, particularly in minority groups. We …

Alzheimer disease (AD) is a common neurodegenerative disease with a late onset. It is
critical to identify novel blood-based DNA methylation biomarkers to better understand the …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

Background: Biological aging may be a robust biomarker of dementia or cognitive
performance. This systematic review synthesized the evidence for an association between …

Importance Variation in DNA methylation at specific loci estimates biological age, which is
associated with morbidity, mortality, and social experiences. Aging estimates known as …

Importance People who complete more education live longer lives with better health. New
evidence suggests that these benefits operate through a slowed pace of biological aging. If …