Parkinson's disease: the non-motor issues

KR Chaudhuri, P Odin, A Antonini… - Parkinsonism & related …, 2011 - Elsevier
Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and
under-researched when taken as a whole. Data is emerging that it is the “totaL” burden of …

Non-motor Parkinson's: integral to motor Parkinson's, yet often neglected

A Todorova, P Jenner, KR Chaudhuri - Practical neurology, 2014 - pn.bmj.com
Non-motor symptoms are a key component of Parkinson's disease, possibly representing a
clinical biomarker of its premotor phase. The burden of non-motor symptoms can define a …

The impact of non‐motor symptoms on health‐related quality of life of patients with Parkinson's disease

P Martinez‐Martin, C Rodriguez‐Blazquez… - Movement …, 2011 - Wiley Online Library
Background: Non‐motor symptoms are detrimental to health‐related quality of life (HRQoL)
of Parkinson's disease patients. In this study, the Non‐Motor Symptoms Scale (NMSS) was …

Nonmotor fluctuations in Parkinson disease: severity and correlation with motor complications

A Storch, CB Schneider, M Wolz, Y Stürwald, A Nebe… - Neurology, 2013 - neurology.org
Objective: To evaluate frequency, severity, and correlation of nonmotor symptoms (NMS)
with motor complications in fluctuating Parkinson disease (PD). Methods: The Multicenter …

Rotigotine effects on early morning motor function and sleep in Parkinson's disease: a double‐blind, randomized, placebo‐controlled study (RECOVER)

C Trenkwalder, B Kies, M Rudzinska, J Fine… - Movement …, 2011 - Wiley Online Library
In a multinational, double‐blind, placebo‐controlled trial (NCT00474058), 287 subjects with
Parkinson's disease (PD) and unsatisfactory early‐morning motor symptom control were …

Plasma p-tau181, neurofilament light chain and association with cognition in Parkinson's disease

L Batzu, S Rota, A Hye, A Heslegrave, D Trivedi… - npj Parkinson's …, 2022 - nature.com
Early identification of cognitive impairment in Parkinson's disease (PD) has important clinical
and research implications. The aim of our study was to investigate the role of plasma tau …

Gender-related differences in the burden of non-motor symptoms in Parkinson's disease

P Martinez-Martin, C Falup Pecurariu, P Odin… - Journal of …, 2012 - Springer
Differences in the expression of non-motor symptoms (NMS) by Parkinson's disease (PD)
patients may have important implications for their management and prognosis. Gender is a …

The impact of non‐motor symptoms on the quality of life of Parkinson's disease patients: a longitudinal study

KM Prakash, NV Nadkarni, WK Lye… - European journal of …, 2016 - Wiley Online Library
Background and purpose Non‐motor symptoms (NMS s) are common amongst patients with
Parkinson's disease (PD); however, little is known about their influence on the health …

Euro I nf: AM ulticenter C omparative O bservational S tudy of A pomorphine and L evodopa I nfusion in P arkinson's D isease

P Martinez‐Martin, P Reddy… - Movement …, 2015 - Wiley Online Library
Subcutaneous apomorphine infusion (Apo) and intrajejunal levodopa infusion (IJLI) are two
treatment options for patients with advanced Parkinson's disease (PD) and refractory motor …

Expanded and independent validation of the movement disorder society–unified Parkinson's disease rating scale (MDS-UPDRS)

P Martinez-Martin, C Rodriguez-Blazquez… - Journal of …, 2013 - Springer
Abstract The Movement Disorder Society-UPDRS (MDS-UPDRS) was published in 2008,
showing satisfactory clinimetric results and has been proposed as the official benchmark …