Chemokines and chemokine receptors: positioning cells for host defense and immunity
JW Griffith, CL Sokol, AD Luster - Annual review of immunology, 2014 - annualreviews.org
Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …
of all immune cells. Although chemokines were initially appreciated as important mediators …
Localization, tissue biology and T cell state—implications for cancer immunotherapy
Tissue localization is a critical determinant of T cell immunity. CD8+ T cells are contact-
dependent killers, which requires them to physically be within the tissue of interest to kill …
dependent killers, which requires them to physically be within the tissue of interest to kill …
Memory T cell subsets, migration patterns, and tissue residence
SN Mueller, T Gebhardt, FR Carbone… - Annual review of …, 2013 - annualreviews.org
Tissues such as the skin and mucosae are frequently exposed to microbial pathogens.
Infectious agents must be quickly and efficiently controlled by our immune system, but the …
Infectious agents must be quickly and efficiently controlled by our immune system, but the …
CXCR3 in T cell function
JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …
CXCR3 ligands: redundant, collaborative and antagonistic functions
JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …
International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for …
F Bachelerie, A Ben-Baruch, AM Burkhardt… - Pharmacological …, 2014 - Elsevier
Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …
The integration of T cell migration, differentiation and function
T cells function locally. Accordingly, T cells' recognition of antigen, their subsequent
activation and differentiation, and their role in the processes of infection control, tumour …
activation and differentiation, and their role in the processes of infection control, tumour …
Phenotype and function of human T lymphocyte subsets: consensus and issues
In recent years, a tremendous effort has been devoted to the detailed characterization of the
phenotype and function of distinct T cell subpopulations in humans, as well as to their …
phenotype and function of distinct T cell subpopulations in humans, as well as to their …
Plasticity of human CD4 T cell subsets
J Geginat, M Paroni, S Maglie, JS Alfen… - Frontiers in …, 2014 - frontiersin.org
Human beings are exposed to a variety of different pathogens, which induce tailored
immune responses and consequently generate highly diverse populations of pathogen …
immune responses and consequently generate highly diverse populations of pathogen …
High endothelial venules (HEVs) in immunity, inflammation and cancer
L Blanchard, JP Girard - Angiogenesis, 2021 - Springer
High endothelial venules (HEVs) are specialized blood vessels mediating lymphocyte
trafficking to lymph nodes (LNs) and other secondary lymphoid organs. By supporting high …
trafficking to lymph nodes (LNs) and other secondary lymphoid organs. By supporting high …